A single‐blind, randomized, pilot study of a brief mindfulness‐based intervention for the endometriosis‐related pain management

De França Moreira, Marcelo, Olga Lucia Gamboa, Olga Lucía Gamboa, Marco Aurelio Pinho Oliveira, Marco Aurélio Pinho Oliveira
European journal of pain (London, England) · 2022 · vol. 26(5) , pp. 1147–1162 · doi:10.1002/ejp.1939 · PMID:35276031 · W4221084776
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A brief mindfulness-based intervention improved endometriosis-related pain and mental health in symptomatic women compared to standard medical treatment alone.

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Abstract

Abstract Background Women with endometriosis suffer from frequent symptoms despite multiple treatments in tertiary care. Although there is a need for a biopsychosocial perspective on endometriosis treatment, few conservative treatments have been investigated. We aimed to investigate the effects of a brief Mindfulness‐Based Intervention (bMBI) in women with deep endometriosis who remain symptomatic despite undergoing conventional medical treatment. Methods A randomized controlled trial was performed with two groups: a standard medical treatment plus bMBI program and only standard medical treatment as a control. A total of 63 eligible participants were randomized to bMBI and control groups. The primary outcome was endometriosis‐related pain, and secondary outcomes were quality of life and stress perception post‐treatment. Analyses were carried out using multiple regression models. Results The results show that bMBI significantly improved pain unpleasantness (Cohen's f 2 = 0.67, NNT = 3.2), pelvic pain (Cohen's f 2 = 0.16, NNT = 5.3) and dyschezia (Cohen's f 2 = 0.23, NNT = 2.9) immediately post‐treatment and decreased all endometriosis‐related pain (Cohen's f 2 ranging from 0.20 to 0.60 and NNT ranging from 5 to −9) after the follow‐up. We found an extensive positive effect of bMBI on the mental health dimension in the two time point measures (Cohen's f 2 = 0.34 and 0.25, NNT = 3.5 and 2.3) and vitality (Cohen's f 2 = 0.22, NNT = 2.1) after the follow‐up. Conclusions Our study suggests that bMBI is useful for managing endometriosis‐related pain and restoring women's psychological well‐being. Significance Brief Mindfulness‐Based Intervention (bMBI) improved endometriosis‐related pain and mental health compared to standard medical care. The present findings contribute to the applicability of MBI in visceral pain patients.

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Condition tags

mesh:D004715mesh:D017699endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Mindfulness Mindfulness Female Female Humans Humans Pain Management Pain Management Pelvic Pain Pelvic Pain Pilot Projects Pilot Projects Quality of Life Quality of Life Single-Blind Method Single-Blind Method

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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