The immunological impact of orthomolecular medicine using bioactive compounds as key factors in endometriosis

Alexandros Vlachos, Simon Vassiliadis
In: Bioactive Compounds in Health and Disease · 2019 · vol. 2(1) , pp. 1 · doi:10.31989/bchd.v2i1.555 · W2911938297
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This review explores how bioactive compounds within orthomolecular medicine may modulate the immune system to target mesenchymal endometriotic stem cells implicated in endometriosis pathogenesis.

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Abstract

Background: Endometriosis, an inflammatory, non-lethal, non-malignant disease, still has unjustified etiology. Among many, the theory dealing with this review claims that a suppressed or incompetent immune system that is totally unable to eradicate the non-hemopoietic mesenchymal endometriotic stem cell (MESC) escapes immune surveillance. As a result, there is migration and invasion of the aforementioned cell to ectopic tissues causing the disease. Keywords: bioactive compounds, functional foods, endometriosis, orthomolecular medicine, mesenchymal endometriotic stem cell (MESC), immune system
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Background

Endometriosis, an inflammatory, non-lethal, non-malignant disease, still has unjustified etiology. Among many, the theory dealing with this review claims that a suppressed or incompetent immune system that is totally unable to eradicate the non-hemopoietic mesenchymal endometriotic stem cell (MESC) escapes immune surveillance. As a result, there is migration and invasion of the aforementioned cell to ectopic tissues causing the disease.

Keywords

bioactive compounds, functional foods, endometriosis, orthomolecular medicine, mesenchymal endometriotic stem cell (MESC), immune system Downloads Published Issue Section License Copyright (c) 2019 Alexandros Vlachos, Simon Vassiliadis This work is licensed under a Creative Commons Attribution 4.0 International License. Authors retain the copyright of their articles and grant the Functional Food Center (FFC) and its journals the right of first publication under the terms of the Creative Commons Attribution 4.0 International License. This license permits unrestricted use, distribution, and reproduction in any medium, including commercial use, provided the original author(s) and source are properly credited. Authors may post and share their published work freely, provided that the original publication in this journal is acknowledged. By submitting to this journal, authors confirm that their manuscripts are original, not under consideration elsewhere, and that they hold the necessary rights to grant this license. The Functional Food Center encourages open scientific exchange and allows derivative and extended works, provided attribution to the original publication is maintained.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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