Long-term Effectiveness of Presacral Neurectomy for the Treatment of Severe Dysmenorrhea Due to Endometriosis

Fulvio Zullo, Zullo F, Stefano Palomba, Errico Zupi, Tiziana Russo, Russo T, Michele Morelli, Morelli M, Teresa Sena, Sena T, Massimiliano Pellicano, Pellicano M, Pasquale Mastrantonio, P Mastrantonio, Mastrantonio P
The Journal of the American Association of Gynecologic Laparoscopists · 2004 · vol. 11(1) , pp. 23–28 · doi:10.1016/s1074-3804(05)60005-9 · PMID:15104826 · W1978634868
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This study investigated the long-term effectiveness of presacral neurectomy in treating severe dysmenorrhea caused by endometriosis.

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Abstract

Study objectiveTo assess the long-term effectiveness of presacral neurectomy (PSN) in women with severe dysmenorrhea due to endometriosis treated with conservative laparoscopic surgical intervention.DesignRandomized, controlled trial (Canadian Task Force classification I).SettingUniversity-affiliated department of obstetrics and gynecology.PatientsOne hundred forty-one sexually active women of reproductive age.InterventionConservative laparoscopic surgery without (group A) or with (group B) PSN.Measurements and main resultsAt entry and 24-months after surgical procedures, cure rates; frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain; and quality of life were evaluated. At follow-up visit, the cure rate was significantly (P<0.05) higher in group B (83.3%) than in group A (53.3%). The frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain were significantly (P<0.05) lower in both groups compared with baseline values, and only severity was significantly (P<0.05) lower in group B. A significant (P<0.05) improvement in quality of life was observed after surgery in both groups and was significantly (P<0.05) increased in group B compared with group A.ConclusionPSN improves long-term cure rates and quality of life in women treated with conservative laparoscopic surgery for severe dysmenorrhea due to endometriosis.

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Condition tags

dysmenorrheadyspareuniaendometriosischronic_pelvic_pain

MeSH descriptors

Denervation Dysmenorrhea Endometriosis Laparoscopy Pelvis Adult Denervation Dysmenorrhea Dysmenorrhea Dyspareunia Dyspareunia Dyspareunia Endometriosis Endometriosis Female Follow-Up Studies Humans Pelvic Pain Pelvic Pain Pelvic Pain

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