Endometrioma and Ovarian Reserve: A Surgical Approach
While endometriomas may have plausible biological effects, they have a negligible detrimental effect on ovarian reserve, but surgical removal acutely impairs ovarian function.
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This chapter reviews evidence on the association between ovarian endometriomas and ovarian reserve, focusing on spontaneous ovulation rates, ovarian reserve markers, and ovarian stimulation/response. It concludes that while there are plausible biological effects on the ovarian cortex around endometriomas, the impact of endometriomas per se on ovarian reserve is not significant, and spontaneous ovulation is not clearly impaired. The chapter emphasizes that surgical excision is associated with acute worsening of ovarian reserve markers and may reduce ovarian response to gonadotropins, but whether this reflects progressive versus long-term impairment remains under investigation, noting uncertainty. This paper is centrally about endometriosis — specifically ovarian endometriomas and their relationship to ovarian reserve and surgical effects.
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References (40)
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