TRATAMENTO CONSERVADOR DA ADENOMIOSE EM PESSOAS PÓS-MENARCA DE 10 A 29 ANOS: REVISÃO SISTEMÁTICA
This systematic review of conservative adenomyosis treatment in 10-29 year olds found that limited data with diagnostic uncertainty and study limitations prevent establishing efficacy, reproductive benefits, or therapeutic hierarchies.
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This systematic review evaluates conservative treatments for adenomyosis in individuals aged 10 to 29 years, distinguishing between cases with confirmed and uncertain diagnoses. The analysis synthesized twenty-eight reports, including one case treated with high-intensity focused ultrasound and hormonal suppression that resulted in uterine rupture during subsequent pregnancy, alongside other studies lacking comparative efficacy data or consistent denominators for recurrence and reproduction. The authors conclude that existing data describe responses and harms but fail to establish comparative efficacy, causal reproductive benefits, or a clear therapeutic hierarchy due to diagnostic uncertainty and study limitations. This paper is centrally about adenomyosis — specifically focusing on conservative management strategies and outcomes in adolescents and young adults.
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