Impaired pathogen-induced autophagy and increased IL-1β and TNFα release in response to pathogenic triggers in secretory phase endometrial stromal cells of endometriosis patients

Sachiko Matsuzaki, Anne-Sophie Gremeau, Anne‐Sophie Grémeau, Jean-Luc Pouly, Jean‐Luc Pouly
Reproductive biomedicine online · 2020 · vol. 41(5) , pp. 767–781 · doi:10.1016/j.rbmo.2020.06.011 · PMID:32978075 · W3037361388
article OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Endometrial stromal cells from endometriosis patients exhibit impaired autophagy and heightened release of IL-1β and TNFα when stimulated with pathogenic triggers.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Autophagy Endometriosis Endometrium Interleukin-1beta Stromal Cells Tumor Necrosis Factor-alpha Adult Autophagy Autophagy Endometriosis Endometrium Endometrium Female Humans Interleukin-1beta Lipopolysaccharides Lipopolysaccharides Poly I-C Poly I-C Stromal Cells

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europepmc
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License: CC0 · commercial use OK