Additional file 1 of Activation of α7 nicotinic acetylcholine receptor retards the development of endometriosis

Hao, Meihua, Liu, Xishi, Guo, Sun-Wei
2022 · doi:10.6084/m9.figshare.20001068 · W6902200376
Lab / animal OA: green CC0
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study evaluated the number of endometriotic lesions in mice treated with PNU-282987, demonstrating that activation of the α7 nicotinic acetylcholine receptor retards endometriosis development.

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Abstract

Additional file 1: SupplementaryFigure S1. Positive andnegative controls for immunohistochemistry. For positive controls, human breastcancer tissues were used for E-cadherin, mouse liver tissues for α-SMA, humanadenomyotic tissue samples for desmin and SM-MHC, and mouse lung tissues for α7nAChR.For negative controls, mouse endometriotic lesions were used. Magnification: 400×;Scale bar: 50 μm. Supplementary Figure S2. Cysticappearance of endometriotic lesions in mouse experiment 1. Lesions seen fromExperiment 2 are similar. Supplementary Figure S3. The number ofendometriotic lesions per mouse was evaluated from the Control, PNU-282987 andMLA groups in mouse experiment 1. Symbols forstatistical significance levels: NS: p>0.05; *: p<0.05;**: p<0.01. SupplementaryFigure S4. H&E staining from endometriotic lesions. Magnification = 200×, scale bar=100 μm. Supplementary Figure S5. The number of endometrioticlesions per mouse was evaluated from the Control and PNU-282987 groups in mouse experiment 2. NS: p>0.05.

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (54)

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