Journal of assisted reproduction and genetics

The aim of this systematic review and meta-analysis was to determine the acceptance rates and reasons for social oocyte cryopreservation (SOC) in the general population (subgroup 1) and healthcare professionals/students (subgroup 2) accordi…

OBJECTIVE: We aimed to compare the effects of the progestin-primed ovarian stimulation (PPOS) protocol and gonadotropin-releasing hormone antagonist (GnRH-A) protocol in women with different ovarian reserves who underwent assisted reproduct…

PURPOSE: This study is to evaluate the effectiveness of a PPOS protocol in poor prognosis patients undergoing IVF with DuoStim and PGT-A versus the conventional protocol with GnRH antagonist. METHODS: Retrospective cohort study encompassin…

PURPOSE: To compare the effects of the gonadotrophin-releasing hormone (GnRH) agonist protocol, GnRH antagonist protocol, progestin-primed ovarian stimulation (PPOS) protocol, and mild stimulation/natural cycle protocol on the cumulative li…

PURPOSE: To investigate whether a premature rise in progesterone at the end of the follicular phase is adversely associated with oocyte quality in IVF cycles. METHODS: A retrospective cohort study including patients less than or equal to 4…

PURPOSE: AMH inhibits hormone production in luteinized granulosa cells (GCs) and stalls ovarian follicle development in vitro and in vivo. We sought to confirm AMH's mechanism of action through SMAD activation and investigate AMH inhibition…

PURPOSE: To explore the impact of seasonal variations on the risks of hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) in women who undergo in vitro fertilization (IVF) treatment. METHODS: We retrospectivel…

OBJECTIVE: To examine the potential association between blastocyst hatching status and pregnancy outcomes following single blastocyst transfer. METHODS: This is a retrospective cohort. We screened all frozen-thawed single blastocyst transf…

PURPOSE: To assess the association of serum vitamin D level and the live birth rate in women undergoing frozen embryo transfer (FET). METHODS: This is a retrospective cohort study involving 1489 infertile women who had frozen embryo transf…

PURPOSE: To evaluate the performance of different embryo transfer (ET) operators in a strictly controlled scenario minimizing potential confounders. METHODS: This single-center retrospective cohort study analyzed vitrified-warmed single eu…

PURPOSE: This study aimed to monitor the expression of B-cell translocation gene 2 (BTG2) in granulosa cells of patients undergoing IVF/ICSI with respect blastocyst quality outcomes. METHODS: We recruited 181 women undergoing IVF/ICSI cycl…

PURPOSE: To evaluate the impact of poor ovarian response (POR) on live birth outcomes in endometriosis patients undergoing IVF/ICSI-ET, despite the expected association between reduced oocyte yield and poorer prognosis. METHODS: Patients w…

PURPOSE: To investigate BMAL1 and BMP6 expressive differences in ovarian granulosa cells (OGCs) of patients with polycystic ovary syndrome (PCOS), explore regulatory relationship, assess their impacts on OGC proliferation and apoptosis, and…

PURPOSE: To compare the prevalence of chronic endometritis (CE) in patients with and without a history of implantation failure and to assess whether CE is associated with BCL6 overexpression or a nonreceptive endometrial receptivity analysi…

OBJECTIVE: Recurrent implantation failure (RIF) is a significant challenge in assisted reproductive technology (ART), affecting many women undergoing in vitro fertilization (IVF). This study aims to compare the efficacy of various intrauter…

PURPOSE: Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with adverse reproductive and obstetric outcomes, particularly in pregnancies achieved through assisted reproductive technologies. This study aimed to compa…

Congenital anomalies (CAs) are a leading cause of perinatal and child mortality. With the increasing use of assisted reproductive technology (ART), there is a growing need for research on the health outcomes of children conceived through AR…

OBJECTIVE: The association between anti-Müllerian hormone (AMH) levels and embryonic aneuploidy rates was investigated by analyzing clinical and embryo laboratory data from patients with preimplantation genetic testing for aneuploidy (PGT-A…

BACKGROUND: Natural cycle in vitro fertilization (NC-IVF) represents a convenient and safe assisted reproductive technology, making it particularly advantageous for patients with poor ovarian response (POR). This research evaluates the effe…

PURPOSE: Recent evidence showed that the phase between pronuclear fading and the first cleavage is a perilous bridge connecting the zygote and the embryo. Indeed, delay in the short interval between pronuclear breakdown (PNBD) and the first…

OBJECTIVE: To evaluate the developmental potential of zygotes without pronucleus (0PN) and to examine the pregnancy outcomes of euploid blastocysts derived from these zygotes. METHODS: A total of 4580 fresh autologous preimplantation genet…

OBJECTIVE: This study aims to develop a machine learning-based predictive model for patients with endometriosis, with the goal of precisely identifying key factors and reliable predictive markers that influence live birth outcomes following…

PURPOSE: The time at which embryo developmental velocity variations occur remains unknown. Therefore, we analysed the morphokinetic trajectory of human early fertilisation from the extrusion of the second polar body (PB2) to pronuclear brea…

PURPOSE: Despite various stimulation protocols and adjuvant treatments, optimizing the reproductive success of women with poor ovarian response (POR) undergoing assisted reproduction techniques (ART) remains a challenge. The aim was to eval…

Egg donation is a procedure that is powerfully advertised as a beneficial experience with limited mention of the associated risks. Egg donor recruitment advertisements target young and financially insecure women and can serve as a catalyst …