Zhonghua fu chan ke za zhi

OBJECTIVE: To compare the efficacy and safety of mifepristone and danazol after conservative surgery in the treatment of patients with endometriosis. METHODS: Sixty-one patients with endometriosis (RAFS stage I-IV ) after conservative surg…

OBJECTIVE: To investigate the regulatory effects of mifepristone and progesterone on the secretion of interleukin-6 (IL-6) by endometrial and endometriosis cells in vitro. METHODS: Primary cultures of eutopic and ectopic endometrial cells …

OBJECTIVE: To study the possibility of a correlation between polymorphism of human leukocyte antigen (HLA)-I antigen and occurrence of endometriosis (Em). METHODS: Polymorphism of HLA-I A and B locations were detected by mini-lymphocytotox…

OBJECTIVE: To investigate the correlation of endometriotic focus and peritoneal fluid as well as its effect on reproduction. METHODS: Forty-three women with surgical treatment or laproscope with infertility are divided into endometriosis g…

OBJECTIVE: To investigate the abnormal distribution of lymphocytes in eutopic and ectopic endometrium of patients with endometriosis and its significance. METHODS: In 43 cases, biopsies of ectopic tissues were taken by laparoscopy and lapa…

OBJECTIVE: To study the changes of tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) levels in peritoneal fluid of patients with endometriosis and their effects on human sperm motility and mouse embryo development. METHODS: …

OBJECTIVE: To study clinicopathologic characteristics, treatment and prognostic factors of malignant transformation of endometriosis of the ovary. METHODS: From 1981 to 1999, a total of 25 patients with malignant transformation of endometr…

OBJECTIVE: To observe the therapeutic effect of Tripterygium wilfordii Hook. f. on patients with uterine leiomyoma. METHODS: Baseline ultrasound examinations of myomas and uterine were obtained and repeated three months, six months after t…

OBJECTIVES: To evaluate the levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) before and after conservative laparoscopic surgery in patients with endometriosis. METHODS: The TNF-alpha and IL-6 levels in serum and p…

OBJECTIVE: To investigate the expression of B cell lymphoma/leukemia-2 (Bcl-2) protein in adenomyosis and its clinical implication. METHODS: Endometrium specimens were obtained from 16 normal uterus and 32 with adenomyosis. bcl-2 expressio…

OBJECTIVE: To study the possible effect of major histocompatibility complex-class I (MHC-I) antigen on endometrial stromal cells in endometriosis patients. METHODS: The stromal cells of endometrium was separated and cultured in vitro. gamm…

OBJECTIVE: To investigate in vitro effect of danazol on cytokine production of macrophages in peritoneal fluid from infertile patients with endometriosis and its relationship with cytosolic free calicum ([Ca2+]i) concentration. METHODS: Pe…

OBJECTIVE: To investigate the relationship between prolactin (PRL) secretion by ectopic endometrial stromal cells and elevated PRL concentrations of peritoneal fluid in patients with endometriosis. METHODS: Twelve samples of each ectopic e…

OBJECTIVE: To investigate the role of cytokines in peritoneal fluid on pathogenesis of endometriosis (EM). METHODS: Interleukin-6 (IL-6), interleukin-8(IL-8) and transforming growth factor-beta 1 (TGF-beta 1) contents in peritoneal fluid (…

OBJECTIVE: To investigate the cytokin production of T helper cell (Th) 1, Th2 subsets in patients with endometriosis(EM). METHODS: The cytokine production of Th1, Th2 cells expressed by interferon-gamma (IFN-gamma) and interleukin-4 (IL-4)…

OBJECTIVE: To study the efficacy and safety of combining domestic luteinizing hormone-releasing hormone analogue(LHRH-a) with low-dose norethindrone in the treatment of endometriosis. METHODS: Seventy-seven women with endometriosis were ra…

OBJECTIVE: To analyse the relationship between endometriosis and epithelial ovarian cancer. METHODS: We analyzed retrospectively the 20 cases associated with endometriosis in 371 cases of epithelial ovarian cancer, and these 20 cases were …

OBJECTIVE: To investigate the clinical significance of monocyte chemotactic protein-1 (MCP-1) produced by endometriotic tissues. METHODS: Expressions of MCP-1 mRNA and MCP-1 protein were determined by dot blot analysis, immunohistochemical…

OBJECTIVE: To study the relationship between integrin beta 3, intracellular adhesion molecule (ICAM) and endometriosis. METHODS: The expression of integrin beta 3 and ICAM protein were determined in 3 batches by immunoblotting method in 15…

OBJECTIVE: To Study the role of gonadotropin releasing hormone agonists (GnRH-alpha) in the treatment of adenomyosis with infertility. METHODS: Adenomyosis was diagnosed under lapososcopy in 4 infertile cases. Meanwhile coexsting endometri…

OBJECTIVE: To study erythrocyte immune function of patients with endometriosis and explore the pathogenesis of endometriosis. METHODS: 38 patients with endometriosis diagnosed by laparoscopy or laparotomy and 21 normal women as the control…