[Evaluation of tumor necrosis factor-alpha and interleukin-6 levels in serum and peritoneal fluid of patients with endometriosis].
article
OA: closed
CC0
⤵ 4 in-corpus citations
AI-generated summary
This study found elevated serum and peritoneal fluid levels of TNF-alpha and IL-6 in endometriosis patients, which decreased significantly after conservative laparoscopic surgery.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
OBJECTIVES: To evaluate the levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) before and after conservative laparoscopic surgery in patients with endometriosis. METHODS: The TNF-alpha and IL-6 levels in serum and peritoneal fluid of 20 endometriotic patients and 10 control patients were determined by radioimmunoassay. RESULTS: Significant parallel relationship existed between the stage of endometriosis and the TNF-alpha and IL-6 levels in serum and peritoneal fluid in endometriosis patients (r values: serum: 0.80, 0.52; peritoneal fluid: 0.79, 0.49, P < 0.05). After clearance of endometriosis foci with laparoscopic conservative surgery, the TNF-alpha and IL-6 levels decreased significantly. CONCLUSION: Measuring TNF-alpha and IL-6 level may have important value in postoperative follow-up, surveillance and evaluation of the effectiveness of surgery.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood (sparse)
Too few in-corpus citations on either side for a chart; here are the lists.
Cited by (4)
- Blood biomarkers for the non-invasive diagnosis of endometriosis 2016
- Recent advances in the understanding of endometriosis: the role of inflammatory mediators in disease pathogenesis and treatment 2016
- Inflammatory MicroRNAs and the Pathophysiology of Endometriosis and Atherosclerosis: Common Pathways and Future Directions Towards Elucidating the Relationship 2022
- Evaluation of Proinflammatory Cytokines Concentrations in Plasma, Peritoneal, and Endometrioma Fluids in Women Operated on for Ovarian Endometriosis-A Pilot Study 2025
Cited by (4)
- Evaluation of Proinflammatory Cytokines Concentrations in Plasma, Peritoneal, and Endometrioma Fluids in Women Operated on for Ovarian Endometriosis-A Pilot Study 2025
- Inflammatory MicroRNAs and the Pathophysiology of Endometriosis and Atherosclerosis: Common Pathways and Future Directions Towards Elucidating the Relationship 2022
- Blood biomarkers for the non-invasive diagnosis of endometriosis 2016
- Recent advances in the understanding of endometriosis: the role of inflammatory mediators in disease pathogenesis and treatment 2016
Source provenance
- europepmc
- last seen: 2026-09-16T06:11:32.772430+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:13:13.417725+00:00
License: CC0
· commercial use OK