New England Journal of Medicine

n engl j med 354;21 www.nejm.org may 25, 2006 e23 A 40-year-old woman with long-standing diabetes presented to the emergency room with fever (temperature, 39.5°C) and diffuse abdominal pain. On admission, she had a distended abdomen with mu…

Two new mouse models have been devised that shed light on the genesis of endometriosis and endometrioid ovarian cancer, suggest drugs for the treatment of endometrioid ovarian cancer, and provide a means of testing them.

Of the 60.2 million women in the United States who were of reproductive age in 1995, about 1.2 million, or 2 percent, had had an infertility-related medical appointment within the previous year, and about 15 percent had received infertility…

Endometriosis is the growth of endometrium outside the uterine cavity or myometrium (endometriotic implants), usually in the peritoneal cavity (Figure 1). The question of how the tissue attains this abnormal placement is controversial, alth…

To the Editor: Manifestations of endometriosis in thoracic organs are very rare.1,2 We describe a case of endometriosis in the thoracic aorta. After an uneventful pregnancy, a 28-year-old woman delivered a healthy girl by elective cesarean …

BACKGROUND: Minimal or mild endometriosis is frequently diagnosed in infertile women. It is often treated by resection or ablation of the lesions, but whether this improves fertility has not been established. We carried out a randomized, co…

To the Editor: Ureteral obstruction is an infrequent but serious complication of pelvic endometriosis. Often, endometriosis is not identified as the cause of the obstruction before surgery. Hormona...

Transvaginal ultrasonography of the endometrium has become an important part of the evaluation of women presenting with abnormal uterine bleeding. It is noninvasive, low in cost, and widely available.1 As described by Langer et al. in this …

Endometriosis is defined as the presence of glandular and stromal endometrial tissue outside the uterus. It occurs most frequently in the reproductive organs, other pelvic viscera, and the peritoneum and is estimated to be present in 3 to 1…

BACKGROUND: Endometrial resection is an alternative to hysterectomy in the treatment of women with menorrhagia, but it may not control the condition. We sought to evaluate the effectiveness of such resection. METHODS: We followed 525 conse…

BACKGROUND: Laparoscopically assisted vaginal hysterectomy has been promoted as a substitute for both abdominal and vaginal hysterectomy, with claimed benefits of lower costs, shorter hospital stays, and quicker postoperative recovery. MET…

Presentation of CaseAn 84-year-old woman was admitted to the hospital because of lymphoma and the recent onset of cough and fever.The patient had been well until 12 years earlier, when well-differentiated lymphocytic lymphoma and thrombocyt…

BACKGROUND: Analogues of gonadotropin-releasing hormone (GnRH) are often given to induce hypogonadism in women who have estrogen-dependent disorders such as endometriosis and uterine leiomyomas. Because estrogen deficiency causes bone loss,…

Each year more than a million American women use infertility services, but fewer than 50 percent of them go on to deliver a live baby1. Standard treatments for infertility include induction of ovulation, artificial insemination, and surgery…

Endometriosis is a common disorder, yet it is among the most enigmatic of gynecologic diseases. The literature on endometriosis is extensive, though often contradictory or inadequate, and reflects our frequent inability to decipher even the…

Presentation of CaseA 34-year-old woman was admitted to the hospital because of low-back and flank pain, with oliguria.The patient was well until seven years earlier, when severe abdominal pain developed, and a laparotomy performed at anoth…

RESEARCH into the neuroendocrine control of reproduction by gonadotropin-releasing hormone (GnRH) has witnessed a remarkable two decades. From the isolation and chemical characterization of GnRH in 1971 through the awarding of the Nobel Pri…