Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 8-1994. An 84-year-old woman with lymphoma, fever, and pulmonary infiltrates

Richard C. Cabot, Robert E. Scully, William F. McNeely, Betty U. McNeely, Richard H. Glew, David L. Swerdlow, Eugene J. Mark
New England Journal of Medicine · 1994 · vol. 330(8) , pp. 557–564 · doi:10.1056/nejm199402243300809 · PMID:8302324 · W2339618384
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This case report describes an 84-year-old woman with a history of lymphocytic lymphoma and idiopathic thrombocytopenic purpura who presented with cough and fever.

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Abstract

Presentation of CaseAn 84-year-old woman was admitted to the hospital because of lymphoma and the recent onset of cough and fever.The patient had been well until 12 years earlier, when well-differentiated lymphocytic lymphoma and thrombocytopenia were diagnosed. She remained well during treatment with cyclophosphamide, vincristine, and prednisone until nine years before admission, when worsening thrombocytopenia was treated by prednisone (up to 80 mg daily) and splenectomy. Microscopical examination of the spleen showed findings consistent with idiopathic thrombocytopenic purpura. Thereafter the patient remained well while taking prednisone (10 mg daily) and danazol.Five years before entry the patient was . . .

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MeSH descriptors

Legionellosis Leukemia, Lymphocytic, Chronic, B-Cell Opportunistic Infections Pneumonia Aged Aged, 80 and over Diagnosis, Differential Female Humans Immunocompromised Host Legionellosis Leukemia, Lymphocytic, Chronic, B-Cell Mycobacterium avium Complex Mycobacterium avium Complex Opportunistic Infections Pneumonia Pneumonia Sputum Sputum

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