European journal of obstetrics, gynecology, and reproductive biology

OBJECTIVE: In this article, we present our initial experience with laparoendoscopic single-site surgery (LESS) for adnexal tumors and report on the safety and feasibility of this technique. STUDY DESIGN: We retrospectively reviewed the med…

OBJECTIVE: The objective of this study was to evaluate the potential treatment of atypical and non-atypical endometrial hyperplasia with the levonorgestrel intrauterine system (LNG-IUS). STUDY DESIGN: A prospective observational study was …

OBJECTIVES: To test the hypothesise that the treatment protocol used for preparation of the endometrium for frozen embryo transfer (ET) has a beneficial effect on the disorganised endometrium in women with endometriosis and leads to a highe…

OBJECTIVE: To assess the outcomes of patients who underwent local excision of adenomyoma and to evaluate the effectiveness of the procedure. STUDY DESIGN: Prospective study of 86 women undergoing local excision of symptomatic uterine adeno…

OBJECTIVE: To investigate factors that might influence the recurrence of both painful symptoms and endometriotic lesions following laparoscopic treatment of endometriosis. STUDY DESIGN: Retrospective cohort study in a University teaching h…

OBJECTIVE: To examine whether long-term administration of dienogest following gonadotropin-releasing hormone agonist (GnRH-a) therapy would prolong the relief of pelvic pain while reducing the amount of irregular uterine bleeding. STUDY DE…

OBJECTIVE: Endometriosis is a multifactorial disease of uncertain etiology. There is currently insufficient evidence to assess the participation of nutritional and anthropometric aspects and their association with systemic oxidative stress.…

OBJECTIVE: The aim of this study was to investigate a possible connection between uterine adenomyosis and the prevalence of symptoms of overactive bladder (OAB), and to study the impact of OAB symptoms on the quality of life (QoL) of women …

Hysteroscopy, hysterosalpingography (HSG), sonohysterography and endometrial ablation are increasingly performed in an outpatient setting. The primary reason for failure to complete these procedures is pain. The objective of this review was…

OBJECTIVE: Endometriosis has been considered an epigenetic disease. Single nucleotide polymorphisms (SNPs) located in genes encoding enzymes of the folate and choline metabolism may affect DNA methyltransferase activity. STUDY DESIGN: We s…

OBJECTIVE: Endometriosis is one of the most frequent gynaecological disorders being associated with infertility. Hence, the early detection of endometriosis in infertility patients is of importance for the treatment modalities in infertilit…

OBJECTIVE: The objectives were: (a) to determine the administrative prevalence and incidence of endometriosis and (b) to assess the risk of endometriosis associated with endometriosis-related symptoms. STUDY DESIGN: The study is based on i…

OBJECTIVE: To determine the efficacy of anti-tumor necrosis factor therapy (etanercept) for treating endometriosis in the rat endometriosis model. STUDY DESIGN: A randomized, placebo-controlled, blinded study using rat endometriosis model.…

OBJECTIVE: To evaluate whether adenomyosis is associated with uterine polyps. STUDY DESIGN: To perform an ethical human study, we planned a large retrospective observational study covering the entire patient population of the ULSS 17-Venet…

OBJECTIVES: The aim of this study is to determine the risk factors for rupture of an ectopic pregnancy (EP) to help physicians identify those women who are at greatest risk. STUDY DESIGN: The study group comprised the cases of EP treated i…

OBJECTIVES: The purpose of this study was to demonstrate the feasibility of single port transumbilical laparoscopic surgery (SPLS) for the treatment of adnexal lesions. METHODS: We have performed SPLS to treat adnexal lesions using a singl…

OBJECTIVE: To evaluate the interaction type of the human uterine relaxant effect of the paracetamol-pyrilamine combination (PPC) in vitro. STUDY DESIGN: Uterine strips were contracted with KCl (60 mM) and treated with vehicle or increasing…

OBJECTIVE: To investigate the effect of uterine adenomyosis diagnosed by transvaginal ultrasound on IVF/ICSI treatment outcome. STUDY DESIGN: A retrospective cohort study of all women aged ≤ 42 years with infertility who underwent IVF/ICSI…

BACKGROUND: Deep infiltrating endometriosis (DIE) is associated with severe painful symptoms and represents a complex management challenge. OBJECTIVE: To analyse the effect of pregnancy on deep infiltrating lesions and related symptomatolo…

OBJECTIVES: Mirena® has been shown to improve symptoms in women with minimal to moderate endometriosis. The precise mechanisms for this have not been thoroughly investigated. We investigate here one possible mechanism-alteration in the numb…

OBJECTIVE: To compare the difficulty of surgery in patients with and without deeply infiltrating endometriosis. STUDY DESIGN: Prospective cohort study performed in one hospital specialized in the surgical treatment of endometriosis. 193 co…

OBJECTIVE: To evaluate the ovarian reserve after laparoscopic stripping of unilateral endometriomas by comparing the operated and non-operated ovaries. STUDY DESIGN: Bilateral ovarian volumes, antral follicle counts, and stromal blood flow…

OBJECTIVE: To study the association of vascular endothelial growth factor (VEGF) polymorphisms (-2578C>A, -1154G>A, -634G>C, and 936C>T) with premature ovarian failure (POF) in Korean patients. STUDY DESIGN: Prospective case-control study.…