Zentralblatt für Gynäkologie

Endometriosis is a chronic debilitating inflammatory disease of women, with the growth of ectopic endometrium in extrauterine sites like rectovaginal septum, peritoneal surfaces, or ovaries, etc. Though endometriosis is not regarded as a ma…

Fluorescence diagnosis and photodynamic therapy with 5-aminolevulinic acid induced protoporphyrin IX are promising new options in the diagnosis and therapy of diseases in a wide spectrum of medical disciplines such as urology, dermatology, …

The significance of retrograde menstruation as a risk factor for endometriosis has been confirmed by numerous clinical observations. Integrins mediate both cell-cell and cell-matrix adhesion, and it is therefore suspected that integrins are…

Bleeding disorders are one of the most frequent gynecological problems. The causes of bleeding disorders, and their frequency in particular, vary depending on the age of the woman affected. In premenopause and perimenopause, the most freque…

Septate uterus is a malformation caused by the defective resorption of the Müllerian ducts. It may be incomplete, or -- less frequently -- complete. We present a case of a uterus septus completus with special emphasis on the endometrial cha…

We report on a 26-year old female patient with thoracic pain and dyspnea, in whom a large tumorous mass in the anterior mediastinum with a pleural effusion was diagnosed by computed tomography and magnetic resonance imaging. After rapid pro…

Ziel: Patientinnen mit Endometriose beschreiben häufig eine Vielzahl von darmassoziierten Symptomen. Ziel ist die Identifizierung einer typischen Symptomatologie bedingt durch eine Rektuminfiltration bei Endometriosepatientinnen.

Clinical pelvic exam, vaginal sonography, and, consequently, laparoscopic and histologic evaluation may be considered the gold standard for the diagnosis of endometriosis. Additional studies, such as cysto- and rectoscopy, rectal endosonogr…

Peristaltic activity of the non-pregnant uterus serves fundamental functions in the early process of reproduction. Hyperperistalsis of the uterus is significantly associated with the development of endometriosis and adenomyosis. In women wi…

Endometriosis seems to be a common fertility barrier which is affected by immunological and local mechanical factors. The established use of assisted reproductive technologies (ART) provides increasing knowledge about folliculogenesis, fert…

The ENZIAN-Score is presented as a new instrument to classify the deep infiltrating endometriosis. Especially the retroperitoneal part of the severe endometriosis is focussed on. In analogy to an oncological staging four different stages ar…

Today GnRH-Analogues are the most effective substances for the regression of endometriosis and endometriosis related complaints. In combination with add-back medication the treatment is effective with only few tolerable side effects. The di…

Widely accepted as an established method in the diagnostic imaging of diseases of the female pelvis, magnetic resonance imaging (MRI) holds promising potential for the diagnosis of endometriosis. This review describes the general prerequisi…

Endometriosis is one of the most common benign proliferative disorders of the female genital tract and occurs in up to 20 % of women, leading to symptoms such as chronic pelvic pain, dyspareunia, dysmenorrhea but also sterility. Although re…

Experiencing and the significance of menstruation could possibly be a decisive factor in your physiology or pathologic physiology, in accordance with blood flow disturbance or endometriosis. Menstruation is a systemic, characteristic experi…

Die Menstruation kann als Inbegriff der weiblichen Physiologie gesehen werden. Beginnend von der Menarche über Schwangerschaft bis hin zur Menopause bestimmt die Blutung das Leben der Frau (mehr oder weniger). Sie unterliegt differenzierten…

Trotz zahlreicher wissenschaftlicher Untersuchungen ist die Pathogenese der Endometriose in ihren zentralen Punkten bis heute ungeklärt. Die aufgestellten Theorien zur Entstehung werden zwar jeweils durch eine Vielzahl klinischer Beobachtun…

Infertility is a common clinical finding in patients with endometriosis. Surgical procedures have shown some benefit, whereas endocrine treatment alone does not improve fertility. Although assisted reproduction is superior to observation on…

Laparoscopy holds a key role in daignosing and treating endometriosis. The present paper aims at clarifying the correct indication for this procedure. To this end, relevant guidelines as well as considerations regarding incidence, pathogene…

Endometriosis is considered a chronic disease of women during their reproductive phase, which resembles many signs of malignancy. So far, therapeutic options for endometriosis-associated pain and infertility are unsatisfactory and often lea…

Endometriosis and adenomyosis show a high prevalence and can be regarded as different symptoms of a unique disease - the dislocation of basal endometrium. Diagnostic methods for detecting adenomyosis are transvaginal sonography (TVS) or T-2…

Fragestellung: Endometriose ist eine der häufigsten gynäkologischen Erkrankungen im reproduktionsfähigen Alter. Diskrepanzen zwischen klinischem Befund und subjektivem Krankheitserleben lassen die Frage nach determinierenden Faktoren für da…

Endometriosis is one of the main illnesses affecting women during their fertile age. Symptoms caused by endometriosis include dysmenorrhea, chronic pelvic pain, dyspareunia, menstrual disorders and infertility. Apart from surgical and medic…

The medical treatment of endometriosis needs to be optimized. Therapeutic management strategies of endometriosis-associated pain or recurrent disease is primarily aimed at downregulating the ovarian function or at antagonizing the effect of…