Journal of pharmaceutical sciences

J Pharm Sci · ISSN (print) 0022-3549 · 5 papers in corpus
2020
doi:10.1016/j.xphs.2020.02.016 ·PMID:32113976

SHetA2 is a new drug with potential to treat cervical dysplasia, but only 0.02% of the dose is absorbed into the cervix after oral administration. By contrast, 23.9% of the dose is absorbed into the cervix after vaginal administration. This…

2018
doi:10.1016/j.xphs.2017.09.018 ·PMID:28989018

Cervical dysplasia induced by the human papilloma virus unpredictably progresses to cervical cancer. Therapeutic options are invasive and affect the patient's quality of life. SHetA2 has demonstrated therapeutic efficacy against human and m…

2018
doi:10.1016/j.xphs.2018.07.009 ·PMID:30031026

Acute pancreatitis (AP) is a serious inflammatory disorder of the pancreas with considerable mortality. The clinical therapy is hampered due to lack of any approved drug for AP. In this study, we developed curcumin (cur)-loaded poly (lactic…

other 2000
doi:10.1002/(SICI)1520-6017(200006)89:6<732::AID-JPS4>3.0.CO;2-D ·PMID:10824131

The objective of these studies was to develop a leuprolide acetate depot based on an in situ forming drug delivery system (Atrigel(R)) to suppress the pituitary-gonadal axis and in turn the serum testosterone to chemical castration levels f…

other 1995
doi:10.1002/jps.2600840810 ·PMID:7500280

The physicochemical properties of A-75998, a synthetic antagonist of luteinizing hormone releasing hormone with potential for treatment of hormone-sensitive cancers and endometriosis, are described. An accelerated solution stability study i…