Rapid Dissolution of High‐Potency Danazol Particles Produced by Evaporative Precipitation into Aqueous Solution

Xiaoxia Chen; Jason M. Vaughn; Miguel José Yacamán; Robert O. Williams; Keith P. Johnston

doi:10.1002/jps.20001

Rapid Dissolution of High‐Potency Danazol Particles Produced by Evaporative Precipitation into Aqueous Solution

Xiaoxia Chen, Jason M. Vaughn, Miguel José Yacamán, Robert O. Williams, Keith P. Johnston

In: Journal of Pharmaceutical Sciences · 2004 · vol. 93(7) , pp. 1867–1878 · doi:10.1002/jps.20001 · PMID:15176074 · W2070875511

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Evaporative precipitation into aqueous solution rapidly produced high-potency danazol particles with improved dissolution properties.

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Cited by (4)

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[1] Solubilization and Wetting Effects of Bile Salts on the Dissolution of Steroids 1991

[2] Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs 1995

[3] Surface treatment of the hydrophobic drug danazol to improve drug dissolution 1998