Wei Y

BACKGROUND: Ovarian clear cell carcinoma (OCCC) is a rare histological subtype of ovarian cancer, often associated with endometrial lesions, and characterized by poor prognosis and a high propensity for recurrence and metastasis. This study…

BACKGROUND: With the increasing use of assisted reproductive technology (ART), more women with endometriosis are achieving pregnancy through ART. However, the impact of endometriosis on pregnancy and perinatal outcomes following ART remains…

BACKGROUND: Sperm DNA fragmentation index (DFI) has emerged as a potential marker of male fertility, but its clinical value in assisted reproductive technology (ART) remains debated. This study aimed to investigate the association between s…

Elagolix sodium (ELS), a non-peptide oral gonadotropin-releasing hormone receptor (GnRH) antagonist approved for the treatment of endometriosis-associated pain, displays atypical gelation in aqueous environments along with challenging physi…

ObjectiveTo analyze the correlation between lipid levels and the severity of polycystic ovary syndrome (PCOS) and its predictive value for pregnancy outcome.MethodsThis retrospective study included 275 PCOS patients treated with ovulation i…

BACKGROUND: Deeply infiltrating endometriosis (DIE), characterized by its extrauterine invasion, is strongly associated with chronic pelvic pain (CPP). Peripheral-central sensitization synergistically contribute to the pathogenesis of CPP i…

IntroductionEmbryonic stem cells (ESCs), capable of generating all adult cell types, hold transformative potential for agriculture and biomedicine. However, stable sheep ESCs derivation remains challenging, limiting their application in fur…

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apop…

Phthalate esters (PAEs) and organophosphate esters (OPEs) are pervasive 20 environmental pollutants with endocrine-disrupting properties. Despite growing 21 evidence linking PAE/OPE exposure to female reproductive disorders, the 22 diseases…

BACKGROUND: With rising rates of delayed childbearing in China, clinical decision-making for advanced-age primiparas (≥ 35 years) is challenging, often leading to unnecessary cesarean sections or failed labor trials. This study aimed to dev…

OBJECTIVE: To assess the safety and efficacy of percutaneous intrauterine hydrodissection as a protective technique during microwave ablation (MWA) of uterine fibroids adjacent to the endometrium. MATERIALS AND METHODS: A retrospective ana…

BackgroundPyometra is an uncommon gynecologic disorder characterized by the accumulation of pus within the uterine cavity typically resulting from cervical obstruction. Spontaneous perforation of pyometra (SPP) is extremely rare but may rap…

Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth rates…

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and its molecular mechanisms rema…

BACKGROUND: Ghrelin, a peptide composed of 28 amino acids, is recognized for its role in regulating appetite and energy balance. Recently, it has also been identified as an immunomodulator that could significantly influence immune responses…

Atherosclerosis (AS) is a systemic disease closely related to inflammatory cell infiltration and immune cell activation, often leading to myocardial infarction and stroke and is the leading cause of death worldwide. AS is asymptomatic in it…

BackgroundThe incidence and fatality rates of chronic obstructive pulmonary disease (COPD) are increasing, and the acute exacerbation of COPD (AECOPD) causes poor prognosis in patients.AimThis study evaluated the clinical role of serum lncR…

Severe acute pancreatitis (SAP) is an inflammatory disease of the pancreas accompanied with intestinal injury, and effective therapeutic modalities are still highly lacking. Herein, a facile and effective nanotherapeutics (pHA@IBNCs) is dev…

BackgroundPlatelet count (PLT) has been identified as a predictor for the development of pelvic adhesions. However, it remains unclear whether platelet-related parameters can also serve as indicators for the occurrence of intrauterine adhes…

This study investigated the relationship between dyslipidemia prior to conception and the risk of preeclampsia (PE) in women pregnant by in vitro fertilization and embryo transfer (IVF-ET). The retrospective cohort study consisted of 2994 w…

Background and objectivesMultimorbidity is increasingly prevalent among the middle-aged population, yet it is largely often overlooked. We aimed to explore and compare the differences in multimorbidity patterns by sex and age among middle-a…

Endometriosis is a complex disorder characterized by genetic, immune, inflammatory, and multifactorial etiologies. Dietary fiber, a crucial component abundant in fruits, vegetables, and whole grains, is known for its diverse beneficial effe…

Abstract Objective To analyze the clinical characteristics of patients with ovarian clear cell carcinoma and to explore the prognostic-related risk factors.Methods We retrospectively analyzed 102 patients diagnosed with ovarian clear cell …

IntroductionObesity has previously been correlated with an elevated risk of reproductive system diseases in women. The waist-hip ratio (WHR) has been shown to be correlated with visceral fat, making it one of the most commonly used indicato…

BACKGROUND: Endometriosis is a complicated and enigmatic disease that significantly diminishes the quality of life for women affected by this condition. Increased levels of human telomerase reverse transcriptase (TERT) mRNA and telomerase a…