Wan G

No ORCID on file · 11 papers in corpus · active 2011-2025

Study types

  • article 7
  • other 4

Condition tags

  • endometriosis 6
  • adenomyosis 5
  • dysmenorrhea 1
other 2025
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01944-1

Adenomyosis (AM), a gynecological disorder that severely affects female reproductive health. AM-associated macrophage (AAM) polarization-induced epithelial-mesenchymal transition (EMT) is a key driver of AM progression. In this study, we in…

other 2025
Inflammation research : official journal of the European Histamine Research Society ... [et al.] ·doi:10.1007/s00011-025-02010-x

Endometriosis, a persistent inflammatory disease, is associated with pelvic or abdominal pain. The immune system and sensory nervous system show a synergistic effect on regulation of pain. In particular, Interleukin-33 (IL-33) is released a…

article 2025
Gene ·doi:10.1016/j.gene.2025.149777

Adenomyosis (AM) is a common non-cancerous condition of the uterus that has significant effects on women's health. Despite its clinical importance, the advancement of dependable non-invasive diagnostic biomarkers has yet to be achieved. Thi…

article 2024
Archives of gynecology and obstetrics ·doi:10.1007/s00404-024-07854-y

PURPOSE: This study aimed to establish a protocol for efficiently isolating and expanding adenomyotic lesion-derived endometrial mesenchymal stem cells (A-eMSCs) in vitro. METHODS: Three different methods-namely, the enzymatic method, the …

article 2024
Journal of ethnopharmacology ·doi:10.1016/j.jep.2024.118724

ETHNOPHARMACOLOGICAL RELEVANCE: Wenshen Xiaozheng Tang (WXT), a traditional Chinese medicine (TCM) decoction, is effective for treating endometriosis. However, the effect of WXT on endometrium-derived mesenchymal stem cells (eMSCs) which pl…

article 2022
Bioengineered ·doi:10.1080/21655979.2022.2077614

This study aimed to identify differentially expressed genes (DEGs) and molecular pathways in eutopic endometrial stromal cells (EuESCs) from adenomyosis (AM) patients and to provide a new insight into the disease mechanisms. The gene expres…

other 2019
Cell communication and signaling : CCS ·doi:10.1186/s12964-019-0361-3

BACKGROUND: Endometriosis, characterized by the presence of functional endometrial tissues outside the uterus, is one of the most common gynecological disorders. Endometrial mesenchymal stem cells (MSCs) are crucial for the occurrence and d…

article 2016
Journal of ethnopharmacology ·doi:10.1016/j.jep.2016.07.019

Ethnopharmacological relevanceWenshen Xiaozheng Tang (WXT), a traditional Chinese medicine prescription, exerted a good therapeutic effect on endometriosis. However, the underlying mechanism is unclear. In the present study, we sought to ev…

other 2014
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.10.050

OBJECTIVE: To investigate the balance between regulatory T cells (Treg) and T-helper 17 cells (T(H)17) in peripheral blood and uteri of women with adenomyosis (AM), and to evaluate their potential correlation with dysmenorrhea and CA-125 le…

article 2013
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113483008

The objective of this study is to investigate the effect of Wenshen Xiaozheng Tang (WXT) on the development of endometriosis in a rat model. Sprague-Dawley rats in which endometriotic implants were induced were divided randomly into 3 group…

article 2011
Journal of ethnopharmacology ·doi:10.1016/j.jep.2011.01.003

Aim of the studyTo investigate the immunological regulation of Guizhi Fuling Capsule (GZFLC) on rat endometriosis.Materials and methodsTwenty-seven rats, in which endometriotic implants were induced by transplanting autologous uterine tissu…