Cell communication and signaling : CCS

Cell Commun Signal · ISSN (e) 1478-811X · 4 papers in corpus
article 2024
Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis
doi:10.1186/s12964-023-01415-7 ·PMID:38291428

BACKGROUND: As a dual-function metabolite, succinate has emerged in cell function and plays a key signaling role in linking mitochondrial function to other cellular functions. Succinate accumulation in the cytoplasm is commonly associated w…

article 2024
The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial–mesenchymal transition by phosphorylating β-catenin
doi:10.1186/s12964-024-01683-x ·PMID:38858740

OBJECTIVES: Interleukin 33 (IL-33) is a crucial inflammatory factor that functions as an alarm signal in endometriosis (EMs). Epithelial-mesenchymal transition (EMT), a process related to inflammatory signals, intracellular reactive oxygen …

review 2023
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology
doi:10.1186/s12964-023-01078-4 ·PMID:36894952

Abstract Gene expression and posttranscriptional regulation can be strongly influenced by epigenetic modifications. N 6 -methyladenosine, the most extensive RNA modification, has been revealed to participate in many human diseases. Recently…

other 2019
Activin a promotes myofibroblast differentiation of endometrial mesenchymal stem cells via STAT3-dependent Smad/CTGF pathway
doi:10.1186/s12964-019-0361-3 ·PMID:31101053

BACKGROUND: Endometriosis, characterized by the presence of functional endometrial tissues outside the uterus, is one of the most common gynecological disorders. Endometrial mesenchymal stem cells (MSCs) are crucial for the occurrence and d…