Johnson MC

No ORCID on file · 8 papers in corpus · active 2004-2026

Study types

  • article 6
  • other 2

Condition tags

  • endometriosis 7
  • infertility 2
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
  • endometrioma 1
other 2026
Estetrol potentiates progesterone-driven growth restraint while blunting pro-angiogenic activation in murine endometriosis lesions
Cells & development ·doi:10.1016/j.cdev.2026.204096

BACKGROUND: Endometriosis is sustained by ectopic endometrial implants that remain proliferative and vascularized, making endocrine modulation a cornerstone of therapy. Estetrol (E4) an endogenous estrogen produced during pregnancy, with se…

article 2015
Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: estradiol regulation
Biological research ·doi:10.1186/s40659-015-0047-2

BACKGROUND: Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protei…

article 2014
Prevalencia de la endometriosis en mujeres sometidas a esterilización quirúrgica laparoscópica en un hospital de Santiago de Chile
Revista medica de Chile ·doi:10.4067/s0034-98872014000100003

BACKGROUND: The clinical manifestations of endometriosis are infertility, dysmenorrhea, sexuality disturbances, and chronic pelvic pain. It is the cause of 30 to 50% of infertility cases. In developed countries, the prevalence of endometrio…

article 2010
P450Arom induction in isolated control endometrial cells by peritoneal fluid from women with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.03.036

ObjectiveTo study the effect of peritoneal fluid from women with (PF-E) and without (PF-C) endometriosis on P(450)Arom expression in endometrial cells.DesignExperimental study.SettingUniversity research unit.Patient(s)Forty women of reprodu…

other 2009
Association between MMP1 and MMP9 activities and ICAM1 cleavage induced by tumor necrosis factor in stromal cell cultures from eutopic endometria of women with endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/REP-09-0196

Endometriosis is a benign gynecological pathology in which immune system deregulation may play a role in its initiation and progression. In endometriotic lesions, intercellular adhesion molecule-1 (ICAM1) is released from the cell membrane …

article 2009
Nuclear factor κB pathway and interleukin-6 are affected in eutopic endometrium of women with endometriosis
Reproduction (Cambridge, England) ·doi:10.1530/rep-08-0407

In order to investigate the role of the nuclear factor kappaB (NFKB) pathway on gene expression in the eutopic endometrium in endometriosis, and in particular of interleukin-6 (IL6), we evaluated RELA, IkappaB kinase (CHUK), NFKBIA and IL6 …

article 2005
Augmented cell survival in eutopic endometrium from women with endometriosis: Expression of c-myc, TGF-beta1 and bax genes
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-3-45

BACKGROUND: Endometriosis is a common gynaecological disorder characterized by the presence of endometrial tissue outside of the uterus. The fragments in normal menstruation are composed of necrotic and living cells, which do not survive in…

article 2004
P450 arom y microambiente estrogénico en endometrios eutópicos de mujeres con endometriosis
Revista medica de Chile ·doi:10.4067/s0034-98872004001200004

BACKGROUND: Endometriosis, a common gynecologic disorder characterized by endometrial glands and stroma outside the uterus, is diagnosed by direct visualization of peritoneal and ovarian implants during laparoscopy. AIM: To study the estrog…