Cells & development

Cells Dev · ISSN (e) 2667-2901 · 1 paper in corpus

other 2026

Estetrol potentiates progesterone-driven growth restraint while blunting pro-angiogenic activation in murine endometriosis lesions

doi:10.1016/j.cdev.2026.204096 ·PMID:42398859

BACKGROUND: Endometriosis is sustained by ectopic endometrial implants that remain proliferative and vascularized, making endocrine modulation a cornerstone of therapy. Estetrol (E4) an endogenous estrogen produced during pregnancy, with se…