Child T

No ORCID on file · 11 papers in corpus · active 2007-2026

Study types

  • article 3

Condition tags

  • endometriosis 3
  • bowel_endometriosis 1
  • infertility 1
2026
Embryo secretome regulation of the endometrial epithelial transcriptome: development of a model to test for embryo viability.
Molecular human reproduction ·doi:10.1093/molehr/gaaf062

The aim of this study was to develop an advanced in vitro model of human endometrium using single-cell-derived endometrial epithelial organoids, enabling the study of embryo secretome-endometrial crosstalk at the maternal-fetal interface. S…

2022
Characterisation of peri-implantation endometrial Treg and identification of an altered phenotype in recurrent pregnancy loss.
Mucosal immunology ·doi:10.1038/s41385-021-00451-1

Recurrent Pregnancy Loss (RPL) affects 2-4% of couples, and with increasing numbers of pregnancy losses the risk of miscarrying a euploid pregnancy is increased, suggesting RPL is a pathology distinct from sporadic miscarriage that is due l…

2022
Elective freezing of embryos versus fresh embryo transfer in IVF: a multicentre randomized controlled trial in the UK (E-Freeze).
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab279

Study questionDoes a policy of elective freezing of embryos, followed by frozen embryo transfer result in a higher healthy baby rate, after first embryo transfer, when compared with the current policy of transferring fresh embryos?Summary a…

2021
A randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI.
Human reproduction (Oxford, England) ·doi:10.1093/humrep/deab041

Study questionWhat is the clinical-effectiveness and safety of the endometrial scratch (ES) procedure compared to no ES, prior to usual first time in vitro fertilisation (IVF) treatment?Summary answerES was safe but did not improve pregnanc…

2021
B Cell Subset Analysis and Gene Expression Characterization in Mid-Luteal Endometrium.
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2021.709280

The human endometrium is the innermost mucosal membrane of the uterus and is the first point of contact for an implanting blastocyst. A wide variety of immune cells are found amongst the endometrial epithelial layers and stromal cells which…

2018
Ovarian response and follow-up outcomes in women diagnosed with cancer having fertility preservation: Comparison of random start and early follicular phase stimulation - cohort study.
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2018.09.007

ObjectivesTo determine response to controlled ovarian stimulation in a random start cycle and utilisation of cryopreserved oocytes and embryos in cancer patients.Study designA retrospective cohort study was carried out in an assisted reprod…

article 2018
The effect of endometriosis on live birth rate and other reproductive outcomes in ART cycles: a cohort study
Human reproduction open ·doi:10.1093/hropen/hoy016

What is the effect of endometriosis compared to unexplained subfertility on live birth rate in women undergoing IVF and embryo transfer (ET)? Endometriosis decreases live birth rate in women undergoing IVF-ET treatment, particularly with in…

2016
Human chorionic gonadotrophin priming for fertility treatment with in vitro maturation.
The Cochrane database of systematic reviews ·doi:10.1002/14651858.cd008720.pub2

BackgroundIn vitro maturation (IVM) is a fertility treatment that involves the transvaginal retrieval of immature oocytes, and their subsequent maturation and fertilisation. Although the live birth rate is lower than conventional in vitro f…

2015
Intrauterine insemination: a UK survey on the adherence to NICE clinical guidelines by fertility clinics.
BMJ open ·doi:10.1136/bmjopen-2015-007588

ObjectiveTo evaluate the awareness and response of fertility clinics in the UK to the National Institute for Health and Care Excellence (NICE) guideline recommendation that intrauterine insemination (IUI) should not be offered routinely, in…

article 2013
Optimising the management of patients with infertility.
The Practitioner

The main causes of infertility are female factor (anovulation, tubal damage, endometriosis and ovarian failure), male factor (low or absent numbers of motile sperm in the ejaculate, and erectile dysfunction), or unexplained infertility. Mor…

article 2007
Urological and colorectal complications following surgery for rectovaginal endometriosis
BJOG: An International Journal of Obstetrics & Gynaecology ·doi:10.1111/j.1471-0528.2007.01477.x

OBJECTIVES: To report the short- and medium-term complications of laparoscopic laser excisional surgery for rectovaginal endometriosis. DESIGN: Retrospective cohort study. SETTING: University teaching hospital, UK. POPULATION: A total of 12…