BMJ open

BMJ Open · ISSN (e) 2044-6055 · 63 papers in corpus
other 2026
doi:10.1136/bmjopen-2025-112291 ·PMID:42049313

INTRODUCTION: The Ablative Technique Options for Preserving fertility in Endometrioma study is a prospective, monocentric clinical study that combines a randomised controlled trial comparing cystectomy and plasma vapourisation for endometri…

other 2026
doi:10.1136/bmjopen-2025-109888 ·PMID:41734921

INTRODUCTION: Endometriosis is a chronic, oestrogen-dependent condition with a wide range of symptoms and comorbidities that significantly affect physical, emotional and psychological well-being, as well as quality of life. Women with endom…

other 2026
doi:10.1136/bmjopen-2025-111928 ·PMID:41881534

INTRODUCTION: Endometriosis is a chronic, inflammatory and oestrogen-dependent disease frequently causing infertility. Assisted reproductive technologies (ART) are often required to achieve pregnancy, especially in women with advanced endom…

other 2025
doi:10.1136/bmjopen-2025-102774 ·PMID:40617615

BACKGROUND: While previous studies have shown an association between anti-Mullerian hormone (AMH) levels and endometriosis, there are limited data on the relationship between AMH levels and age among women with endometriosis. OBJECTIVES: T…

other 2025
doi:10.1136/bmjopen-2025-105315 ·PMID:40973368

INTRODUCTION: Most clinical practice guidelines (CPGs) for assessing and managing people's chronic pain focus on specific pain conditions, body sites or life course stages. This creates complexity for clinicians making care choices in the a…

other 2025
doi:10.1136/bmjopen-2024-097872 ·PMID:41033777

INTRODUCTION: Endometriosis is a chronic condition affecting up to 11% of people presumed female at birth by the age of 44 years, characterised by the growth of tissue similar to the lining of the uterus on other organs. Endometriosis signi…

other 2025
doi:10.1136/bmjopen-2024-097372 ·PMID:40044193

INTRODUCTION: Endometriosis affects 10-15% of people assigned female at birth and can cause chronic pelvic pain and impair many domains of quality of life, such as fertility, mood and bladder, bowel and sexual function. Current treatments o…

other 2025
doi:10.1136/bmjopen-2025-108596 ·PMID:41436256

INTRODUCTION: Endometriosis is a common, benign, chronic inflammatory disease with multiple consequences, from chronic pain to systemic comorbidities and poor quality of life. As it usually affects people of reproductive age, one of the mos…

other 2025
doi:10.1136/bmjopen-2025-100273 ·PMID:40774701

INTRODUCTION: Dysmenorrhoea (period pain) is a global public health issue affecting up to 91% of the 1.8 billion individuals who menstruate. While research has emphasised the improvement of menstrual health in low-middle-income countries, u…

other 2025
doi:10.1136/bmjopen-2025-105382 ·PMID:41238366

INTRODUCTION: Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice…

other 2025
doi:10.1136/bmjopen-2025-102697 ·PMID:41263886

BACKGROUND: Chronic pelvic pain, defined as persistent pain in the structures of the pelvis, is a condition that significantly impacts the health-related quality of life (HRQoL) of up to one-third of people worldwide, with substantial assoc…

other 2025
doi:10.1136/bmjopen-2025-099374 ·PMID:40866063

OBJECTIVE: To develop and validate models to predict which endometriosis patients are likely to experience pain reduction following therapeutic laparoscopy using intraoperative findings and patient characteristics. DESIGN: A retrospective …

article 2025
doi:10.1136/bmjopen-2025-108125 ·PMID:41314847

INTRODUCTION: Endometriosis affects 5-10% of women during reproductive years, with a 20-30% incidence among those with infertility. Deep infiltrating endometriosis (DIE) affects 10-15% of women of childbearing age and 50% of infertile women…

other 2025
doi:10.1136/bmjopen-2025-100357 ·PMID:40796221

OBJECTIVE: To examine the impact of the COVID-19 pandemic on the substitution of surgical procedures in benign gynaecology in the Netherlands. DESIGN: Quantitative longitudinal study evaluating the effects of the COVID-19 pandemic. SETTIN…

other 2025
doi:10.1136/bmjopen-2025-103140 ·PMID:41073125

BACKGROUND: Endometriosis is a chronic gynaecological condition affecting 2%-10% of women worldwide, often leading to severe pain, organ dysfunction and infertility. Despite its prevalence, diagnosis is frequently delayed, and treatment opt…

other 2025
doi:10.1136/bmjopen-2024-087122 ·PMID:39832979

OBJECTIVES: Uterine adenomyosis is a common gynaecological disease that can be debilitating. It is poorly understood and may be overlooked in clinical settings. A research gap exists as there are currently no published scoping reviews on pe…

other 2025
doi:10.1136/bmjopen-2024-091813 ·PMID:39843375

INTRODUCTION: Early pregnancy care involves the screening and identification of women with risk factors for adverse pregnancy outcomes, including stillbirth or preterm birth, to tailor pregnancy care and interventions accordingly. Most stil…

rct 2024
doi:10.1136/bmjopen-2024-088072 ·PMID:39653562

OBJECTIVES: To evaluate the cost-effectiveness of long-acting progestogens (LAP), including levonorgestrel-releasing intrauterine system (LNG-IUS) and depot-medroxyprogesterone acetate (DMPA), compared with the combined oral contraceptives …

other 2024
doi:10.1136/bmjopen-2024-091378 ·PMID:39414291

INTRODUCTION: Reproductive hormone transitions (menstrual cycle, post partum and menopause) can trigger mental disorders in a subset of women. Gynaecological diseases, such as endometriosis and polycystic ovary syndrome, can also elevate th…

meta-analysis 2024
doi:10.1136/bmjopen-2023-077025 ·PMID:39025820

OBJECTIVES: Pregnancy outcomes of different ovarian stimulation protocols for in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) in patients with adenomyosis are not explicit. This meta-analysis aimed to systematically evalu…

article 2024
doi:10.1136/bmjopen-2023-074488 ·PMID:38216177

Objectives We aimed to explore the epidemiological characteristics of suspected adenomyosis within a physical examination population in China. Design A retrospective, nested case-control study; we matched healthy people and those with poten…

other 2024
doi:10.1136/bmjopen-2023-080989 ·PMID:38684268

INTRODUCTION: Endometriosis is a prevalent gynaecological condition for women of reproductive age worldwide. While endometriosis primarily involves the reproductive system, it can also infiltrate additional viscera such as the gastrointesti…

other 2024
doi:10.1136/bmjopen-2023-075316 ·PMID:38238180

INTRODUCTION: Uterine adenomyosis is a benign gynaecological disease that causes physical and psychological problems, impacting on relationships. It is poorly understood and consequently may be diagnosed late. This protocol describes the pr…

article 2023
doi:10.1136/bmjopen-2022-067497 ·PMID:36599637

INTRODUCTION: Overall, 20%-30% of women with endometriosis report endometriosis-related disability after successful laparoscopy. This indicates a potential impact of psychological factors, such as expectations, on treatment outcomes. It is …

other 2023
doi:10.1136/bmjopen-2023-076390 ·PMID:37844983

BACKGROUND: Uterine contractions may interfere with embryo implantation in assisted reproductive technology. To reduce these contractions and improve success rates, the oxytocin antagonist atosiban has been suggested for administration duri…