BMJ open

BMJ Open · ISSN (e) 2044-6055 · 284 papers in corpus
2026
doi:10.1136/bmjopen-2025-112126 ·PMID:42191199

IntroductionAdnexal surgery is one of the most common surgeries performed in women. Minimally invasive methods are on the rise globally as they have been shown to decrease surgical morbidity compared with abdominal surgery. Adnexal surgery …

2026
doi:10.1136/bmjopen-2025-115665 ·PMID:42624608

ObjectivesTo assess the impact of non-communicable diseases (NCDs) by number and pattern on productivity loss costs (PLCs) and health-related quality of life (HRQoL) in a large working-age population in Japan.DesignCross-sectional analysis …

other 2026
doi:10.1136/bmjopen-2025-112291 ·PMID:42049313

INTRODUCTION: The Ablative Technique Options for Preserving fertility in Endometrioma study is a prospective, monocentric clinical study that combines a randomised controlled trial comparing cystectomy and plasma vapourisation for endometri…

2026
doi:10.1136/bmjopen-2025-111265 ·PMID:41605576

IntroductionUnexplained infertility affects about 30% of couples seeking help for infertility, yet the optimal ovulation induction strategy remains largely unclear. Letrozole, clomiphene citrate and gonadotropins are widely used, alone or i…

2026
doi:10.1136/bmjopen-2024-090247 ·PMID:41840742

ObjectiveTo evaluate the cost-effectiveness of the levonorgestrel intrauterine system (LNG-IUS) compared with hysteroscopic niche resection (HNR) for women with niche-related postmenstrual spotting.DesignEconomic evaluation from a healthcar…

2026
doi:10.1136/bmjopen-2025-113914 ·PMID:42392633

BackgroundMenstrual health (MH) is vital to women's overall health and well-being. Yet many women, especially in resource-limited settings, face challenges due to insufficient resources and support. Most MH research has focused on school-go…

other 2026
doi:10.1136/bmjopen-2025-109888 ·PMID:41734921

INTRODUCTION: Endometriosis is a chronic, oestrogen-dependent condition with a wide range of symptoms and comorbidities that significantly affect physical, emotional and psychological well-being, as well as quality of life. Women with endom…

2026
doi:10.1136/bmjopen-2025-115285 ·PMID:42567635

ObjectivesThe relationship between clomiphene citrate (CC) dosing regimens and adverse reproductive outcomes has not been fully elucidated, both with and without use of in vitro fertilisation (IVF). We aimed to study the association between…

rct 2026
doi:10.1136/bmjopen-2026-116964 ·PMID:42191188

INTRODUCTION: Treatment for women with endometriosis is only partially or temporarily effective. Moreover, medical hormonal treatment is associated with debilitating side effects and interferes with fertility, while surgery has a relatively…

article 2026
doi:10.1136/bmjopen-2025-114124 ·PMID:42624581

INTRODUCTION: Endometriosis is associated with reduced pregnancy and live birth rates in patients attempting both spontaneous and assisted conception. At present, it is unclear whether prepregnancy surgery for moderate or severe endometrios…

other 2026
doi:10.1136/bmjopen-2025-111928 ·PMID:41881534

INTRODUCTION: Endometriosis is a chronic, inflammatory and oestrogen-dependent disease frequently causing infertility. Assisted reproductive technologies (ART) are often required to achieve pregnancy, especially in women with advanced endom…

2026
doi:10.1136/bmjopen-2025-111270 ·PMID:41922060

ObjectivesThe research explored how individuals experience chronic pain within their everyday social contexts over a 12-month period. The study focused on the interplay between pain and social worlds, through analysis of experiences of soci…

article 2026
doi:10.1136/bmjopen-2026-121990 ·PMID:42692504

BACKGROUND: Endometriosis affects approximately one in seven women in Australia and is associated with substantial physical, psychological and social impacts. Informational support is critical for enabling informed decision-making and foste…

2026
doi:10.1136/bmjopen-2025-101527 ·PMID:42398988

IntroductionInnovative clinical trials, including adaptive and Bayesian designs, can improve efficiency and prioritise patient-centric approaches. Despite their recognised advantages, the global adoption of innovative clinical trial designs…

2026
doi:10.1136/bmjopen-2025-112480 ·PMID:42567631

ObjectivesThis study estimates the cost of managing infertility, including intrauterine insemination (IUI) from health system perspective in India.DesignThis was a retrospective cross-sectional microcosting study using mixed approach. Unit …

2026
doi:10.1136/bmjopen-2026-123353 ·PMID:42731840

IntroductionChronic pain is a leading public health problem, impacting over 1.5 billion people worldwide. Standard-of-care includes pharmaceutical medication, surgery and physical therapy, yet many patients experience continued symptoms. In…

2026
doi:10.1136/bmjopen-2025-103421 ·PMID:41916631

ObjectivesTo investigate the knowledge, attitudes and practices (KAP) regarding mammary gland hyperplasia (MGH) in adult women from Shandong province, China.DesignA cross-sectional study.SettingThis study was conducted in Shandong province,…

2026
doi:10.1136/bmjopen-2025-110262 ·PMID:42481196

ObjectivesThe focus of the present study is to highlight and understand the effect of hysterectomy on physical, psychological, social and marital status among women aged under 40 years of age, in the cultural context of Pakistan DESIGN: The…

2026
doi:10.1136/bmjopen-2024-097959 ·PMID:42082250

ObjectivesThere is evidence that treatment expectations predict treatment outcomes in pain management and other clinical conditions. However, translating these insights into clinical practice remains challenging: it is difficult to measure …

2026
doi:10.1136/bmjopen-2026-118954 ·PMID:42552011

IntroductionChronic non-specific knee pain represents a prevalent and disabling musculoskeletal condition that often lacks a clearly identifiable structural cause and evidence-based management strategies. Photobiomodulation therapy combined…

2026
doi:10.1136/bmjopen-2026-123210 ·PMID:42680495

IntroductionPremenstrual symptoms occur on a continuum from mild experiences to clinically significant, menstrual cycle-related mood disorders, including premenstrual dysphoric disorder (PMDD). Stress has been implicated as a key pathophysi…

2026
doi:10.1136/bmjopen-2026-117740 ·PMID:42457424

ObjectivesThis study examines heterogeneity in women's use of reproductive healthcare services before and after receiving an infertility diagnosis and its association with pregnancy identified without recorded loss within one year following…

2026
doi:10.1136/bmjopen-2026-116361 ·PMID:42366011

ObjectiveWomen with premenstrual disorder (PMD) display heightened sensitivity to hormonal changes and may be at risk for psychiatric disorders during other hormonally dynamic periods such as pregnancy and postpartum. While PMD has been lin…

2026
doi:10.1136/bmjopen-2025-103971 ·PMID:41748178

IntroductionAdhesive capsulitis of the shoulder is a common shoulder disease. With the ageing population, the incidence of adhesive capsulitis has been rising year by year, posing a significant threat to the quality of life of middle-aged a…

2026
doi:10.1136/bmjopen-2026-117233 ·PMID:42463186

PurposeThe Developmental Origin of Health and Disease framework emphasises the intergenerational influence of both maternal and paternal factors on the perinatal and longer-term outcomes of offspring. Aboriginal and Torres Strait Islander c…