BMJ open

BMJ Open · ISSN (e) 2044-6055 · 290 papers in corpus
2026
doi:10.1136/bmjopen-2025-103971 ·PMID:41748178

IntroductionAdhesive capsulitis of the shoulder is a common shoulder disease. With the ageing population, the incidence of adhesive capsulitis has been rising year by year, posing a significant threat to the quality of life of middle-aged a…

observational 2026
doi:10.1136/bmjopen-2026-117233 ·PMID:42463186

PURPOSE: The Developmental Origin of Health and Disease framework emphasises the intergenerational influence of both maternal and paternal factors on the perinatal and longer-term outcomes of offspring. Aboriginal and Torres Strait Islander…

review 2026
doi:10.1136/bmjopen-2025-114764 ·PMID:42805645

OBJECTIVES: Endometriosis affects 5-10% of women of reproductive age and is associated with chronic pain, infertility and reduced quality of life. Symptom Reporting Tools (SRTs) may support identification and management in primary care, but…

other 2026
doi:10.1136/bmjopen-2026-120614 ·PMID:42547233

INTRODUCTION: Dysmenorrhoea is one of the most frequent manifestations of chronic pelvic pain. Endometriosis and adenomyosis are among the most common pathological causes of secondary dysmenorrhoea. Symptoms often persist despite treatment,…

other 2026
doi:10.1136/bmjopen-2026-122003 ·PMID:42624590

BACKGROUND: Cardiovascular disease risk accelerates in women after the menopausal transition, coinciding with the cessation of endogenous oestrogen production. The accompanying decline in vascular function is considered a key driver of this…

qualitative 2025
doi:10.1136/bmjopen-2024-092542 ·PMID:40889983

OBJECTIVES: To engage individuals with lived experiences of dyspareunia in a co-design process to identify strategies for reducing stigma on digital health platforms. METHOD: Three virtual co-design workshops were conducted with 14 partici…

other 2025
doi:10.1136/bmjopen-2024-098500 ·PMID:40954081

INTRODUCTION: Chronic endometritis (CE) is regarded as a potential factor contributing to infertility and embryo implantation failure. The cause of CE remains unclear at present, but it might be associated with intrauterine microbial infect…

other 2025
doi:10.1136/bmjopen-2024-093959 ·PMID:40345684

INTRODUCTION: The burden of gynaecological diseases is increasing globally, affecting women's health, quality of life and fertility. Improving the quality of gynaecological care will enhance patient recovery and improve outcomes of gynaecol…

observational 2025
doi:10.1136/bmjopen-2025-102774 ·PMID:40617615

BACKGROUND: While previous studies have shown an association between anti-Mullerian hormone (AMH) levels and endometriosis, there are limited data on the relationship between AMH levels and age among women with endometriosis. OBJECTIVES: T…

observational 2025
doi:10.1136/bmjopen-2024-094770 ·PMID:40180417

OBJECTIVE: This study aimed to investigate the relationship between endometrial echo and pregnancy outcome in patients undergoing thawed embryo transfer and explore the effect of different endometrial preparation schemes on endometrial echo…

meta-analysis 2025
doi:10.1136/bmjopen-2025-098850 ·PMID:41309461

OBJECTIVES: Tuberculosis (TB) is a common cause of infertility in humans, especially in regions with high TB prevalence. However, the impact of latent TB infection (LTBI) on pregnancy outcomes following assisted reproduction in patients wit…

observational 2025
doi:10.1136/bmjopen-2024-093237 ·PMID:39762103

OBJECTIVES: To investigate the association between primary dysmenorrhoea and quality of life, mental health and academic performance among medical students in Indonesia. DESIGN: A cross-sectional study using an online survey was conducted …

qualitative 2025
doi:10.1136/bmjopen-2025-104730 ·PMID:41407410

OBJECTIVES: To explore the experience and impact of physical chronic illnesses in the lives of young people. DESIGN: Qualitative study using semi-structured interviews. SETTING: Interviews were conducted between March 2023 and February 20…

other 2025
doi:10.1136/bmjopen-2025-105315 ·PMID:40973368

INTRODUCTION: Most clinical practice guidelines (CPGs) for assessing and managing people's chronic pain focus on specific pain conditions, body sites or life course stages. This creates complexity for clinicians making care choices in the a…

meta-analysis 2025
doi:10.1136/bmjopen-2024-092006 ·PMID:39880438

OBJECTIVE: The presence of the microcystic elongated and fragmented (MELF) pattern, distinguished by its microcystic, elongated and fragmented attributes, constitutes a common manifestation of myometrial invasion (MI) within endometrial car…

other 2025
doi:10.1136/bmjopen-2024-097872 ·PMID:41033777

INTRODUCTION: Endometriosis is a chronic condition affecting up to 11% of people presumed female at birth by the age of 44 years, characterised by the growth of tissue similar to the lining of the uterus on other organs. Endometriosis signi…

rct 2025
doi:10.1136/bmjopen-2024-096265 ·PMID:40473285

OBJECTIVE: To compare recovery after laparoscopic hysterectomy (LH) and abdominal hysterectomy (AH). DESIGN: A parallel, open, non-inferiority, multicentre, randomised controlled, expertise-based surgery trial. SETTING: 10 NHS (National H…

other 2025
doi:10.1136/bmjopen-2024-097372 ·PMID:40044193

INTRODUCTION: Endometriosis affects 10-15% of people assigned female at birth and can cause chronic pelvic pain and impair many domains of quality of life, such as fertility, mood and bladder, bowel and sexual function. Current treatments o…

other 2025
doi:10.1136/bmjopen-2024-096896 ·PMID:40335141

INTRODUCTION: To assess the effects of oral dydrogesterone on the recurrence rate of endometrial polyps (EPs) and abnormal uterine bleeding (AUB) symptoms after transcervical resection of polyps (TCRP). METHODS AND ANALYSIS: A randomised, …

other 2025
doi:10.1136/bmjopen-2025-108596 ·PMID:41436256

INTRODUCTION: Endometriosis is a common, benign, chronic inflammatory disease with multiple consequences, from chronic pain to systemic comorbidities and poor quality of life. As it usually affects people of reproductive age, one of the mos…

other 2025
doi:10.1136/bmjopen-2024-093683 ·PMID:40578878

INTRODUCTION: Thin endometrium poses a major therapeutic challenge in assisted reproductive technologies by compromising pregnancy success and live birth outcomes. A substantial proportion of patients remain refractory to existing therapies…

observational 2025
doi:10.1136/bmjopen-2024-098692 ·PMID:40681192

PurposeTuberculosis (TB) is a significant factor contributing to infertility. For some infertile patients, chest radiography (CXR) screenings prior to assisted reproductive treatment (ART) reveal old/inactive TB lesions. However, the pregna…

rct 2025
doi:10.1136/bmjopen-2025-104789 ·PMID:41047274

INTRODUCTION: Photobiomodulation therapy (PBMT), particularly when combined with a static magnetic field (PBMT-sMF), is a promising non-pharmacological approach for managing musculoskeletal disorders. However, high-quality evidence for its …

other 2025
doi:10.1136/bmjopen-2024-091649 ·PMID:39843366

INTRODUCTION: Premenstrual dysphoric disorder (PMDD) is a cyclic mood disorder affecting around 2%-5% of women of reproductive age. Pharmacological interventions exist, but many patients with PMDD experience residual symptoms, discontinue m…

other 2025
doi:10.1136/bmjopen-2025-106700 ·PMID:41436262

INTRODUCTION: Self-management is essential for girls, women and individuals assigned female at birth (AFAB) living with chronic physical health conditions. Evidence suggests that symptom monitoring can support self-management and empower in…