BMJ open

BMJ Open · ISSN (e) 2044-6055 · 291 papers in corpus
other 2025
doi:10.1136/bmjopen-2025-106700 ·PMID:41436262

INTRODUCTION: Self-management is essential for girls, women and individuals assigned female at birth (AFAB) living with chronic physical health conditions. Evidence suggests that symptom monitoring can support self-management and empower in…

other 2025
doi:10.1136/bmjopen-2025-100273 ·PMID:40774701

INTRODUCTION: Dysmenorrhoea (period pain) is a global public health issue affecting up to 91% of the 1.8 billion individuals who menstruate. While research has emphasised the improvement of menstrual health in low-middle-income countries, u…

other 2025
doi:10.1136/bmjopen-2025-100964 ·PMID:40659407

BACKGROUND: The prevalence of women with primary dysmenorrhoea is high and negatively impacts physical and mental health. The intense cyclic episodes of pain generate central nervous system dysfunctional processing. In this sense, strategie…

observational 2025
doi:10.1136/bmjopen-2025-105694 ·PMID:41309471

OBJECTIVES: To determine whether hormonal contraceptives are associated with subsequent risks of suicidal behaviour and depression among women of reproductive age. DESIGN: Nationwide register-based study. SETTING: Swedish national populat…

other 2025
doi:10.1136/bmjopen-2024-091053 ·PMID:39773807

INTRODUCTION: Exposure to adverse childhood experiences (ACEs) is associated with a range of poor long-term health outcomes, including multimorbidity and chronic pain. Epidemiological evidence underpins much of this relationship; however, p…

observational 2025
doi:10.1136/bmjopen-2024-089499 ·PMID:40044195

OBJECTIVES: This study aimed to investigate the association and population-attributable fraction (PAF) of maternal smoking and secondhand smoke (SHS) exposure during pregnancy with placental abruption. DESIGN: Prospective cohort study. SE…

observational 2025
doi:10.1136/bmjopen-2024-088537 ·PMID:40010827

OBJECTIVES: Dysmenorrhoea, characterised by severe menstrual cramps, affects between 50% and 90% of women of reproductive age and considerably lowers their quality of life. DESIGN: Cross-sectional study. SETTING: This study explored the i…

other 2025
doi:10.1136/bmjopen-2025-105382 ·PMID:41238366

INTRODUCTION: Endometriosis, a chronic oestrogen-dependent disorder, presents significant clinical challenges including pelvic pain, dysmenorrhoea, dyspareunia and infertility. While numerous interventions exist, evidence guiding the choice…

rct 2025
doi:10.1136/bmjopen-2025-106024 ·PMID:41263919

OBJECTIVE: To investigate whether treatment with oral corticosteroids and intravenous immunoglobulin (IVIg) improves pregnancy outcomes in women with unexplained recurrent pregnancy loss (RPL) following assisted reproduction technology (ART…

observational 2025
doi:10.1136/bmjopen-2024-088143 ·PMID:39819913

INTRODUCTION: Despite the global prevalence of low fertility rates, male contributions to fertility and reproductive health outcomes have been understudied. This study aims to investigate the male contribution to fertility and explore the u…

observational 2025
doi:10.1136/bmjopen-2024-096425 ·PMID:41027695

OBJECTIVE: The primary objective of this study is to investigate the perceived need and attitudinal perspectives regarding menstrual leave policies among young women in rural South India. The secondary objective was to determine the socio-d…

other 2025
doi:10.1136/bmjopen-2025-102697 ·PMID:41263886

BACKGROUND: Chronic pelvic pain, defined as persistent pain in the structures of the pelvis, is a condition that significantly impacts the health-related quality of life (HRQoL) of up to one-third of people worldwide, with substantial assoc…

rct 2025
doi:10.1136/bmjopen-2024-095069 ·PMID:40233954

OBJECTIVES: To assess the feasibility of conducting a pragmatic, multicentre randomised controlled trial (RCT) to test the clinical and cost-effectiveness of a pain management training intervention to support people with persistent musculos…

observational 2025
doi:10.1136/bmjopen-2024-089734 ·PMID:39832960

OBJECTIVES: This study aimed to dissect the aetiological subgroups of postpartum haemorrhage (PPH) that occur after vaginal delivery in women with full-term singleton pregnancies. Our goal was to craft and validate predictive models to guid…

other 2025
doi:10.1136/bmjopen-2024-093704 ·PMID:40204320

INTRODUCTION: Weight loss is often recommended as the primary intervention for infertility in individuals with high body mass index. However, focusing on body mass index might overlook other important factors like cardiometabolic health. Th…

observational 2025
doi:10.1136/bmjopen-2025-099374 ·PMID:40866063

OBJECTIVE: To develop and validate models to predict which endometriosis patients are likely to experience pain reduction following therapeutic laparoscopy using intraoperative findings and patient characteristics. DESIGN: A retrospective …

observational 2025
doi:10.1136/bmjopen-2024-097807 ·PMID:40374220

OBJECTIVES: To estimate the prevalence of urinary incontinence (UI) and its subtypes among nulliparous Chinese women with associated risk factors. The prevalence of UI among those living in urban or rural communities was also analysed with …

other 2025
doi:10.1136/bmjopen-2025-103174 ·PMID:41298256

INTRODUCTION: Minimally invasive techniques have been widely adopted for hysterectomy, including Transumbilical Laparoendoscopic Single-Site Surgery (TU-LESS) and Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES). Howeve…

meta-analysis 2025
doi:10.1136/bmjopen-2024-093072 ·PMID:40467315

OBJECTIVE: Surgical site infections (SSI) after hysterectomy constitute significant postoperative complications, affecting patient recovery and healthcare costs. We conducted a systematic review of risk factors for SSI in patients undergoin…

other 2025
doi:10.1136/bmjopen-2025-108125 ·PMID:41314847

INTRODUCTION: Endometriosis affects 5-10% of women during reproductive years, with a 20-30% incidence among those with infertility. Deep infiltrating endometriosis (DIE) affects 10-15% of women of childbearing age and 50% of infertile women…

other 2025
doi:10.1136/bmjopen-2024-091299 ·PMID:40010839

INTRODUCTION: Intrauterine adhesions (IUAs) are one of the most common causes of uterine infertility. Hysteroscopic adhesiolysis is the primary treatment for IUA, but the rate of IUA recurrence is high in moderate to severe cases. While tra…

observational 2025
doi:10.1136/bmjopen-2025-100357 ·PMID:40796221

OBJECTIVE: To examine the impact of the COVID-19 pandemic on the substitution of surgical procedures in benign gynaecology in the Netherlands. DESIGN: Quantitative longitudinal study evaluating the effects of the COVID-19 pandemic. SETTIN…

other 2025
doi:10.1136/bmjopen-2025-103140 ·PMID:41073125

BACKGROUND: Endometriosis is a chronic gynaecological condition affecting 2%-10% of women worldwide, often leading to severe pain, organ dysfunction and infertility. Despite its prevalence, diagnosis is frequently delayed, and treatment opt…

qualitative 2025
doi:10.1136/bmjopen-2024-091182 ·PMID:40228851

OBJECTIVES: To explore how backlogs in health and social care were perceived by and impacted disabled people from minoritised ethnic groups, with a view to improving their experiences and social, health and well-being outcomes. DESIGN: Int…

other 2025
doi:10.1136/bmjopen-2024-085292 ·PMID:40262956

INTRODUCTION: A quarter of women experience heavy periods in their lifetime, often significantly impairing their well-being, productivity and quality of life.Several treatment options are offered for heavy menstrual bleeding; however, there…