BMJ open

BMJ Open · ISSN (e) 2044-6055 · 292 papers in corpus
other 2025
doi:10.1136/bmjopen-2024-085292 ·PMID:40262956

INTRODUCTION: A quarter of women experience heavy periods in their lifetime, often significantly impairing their well-being, productivity and quality of life.Several treatment options are offered for heavy menstrual bleeding; however, there…

qualitative 2025
doi:10.1136/bmjopen-2024-093696 ·PMID:40473293

BACKGROUND: Adolescent girls living in low-income urban informal settlements face unique challenges that elevate their susceptibility to early childbearing. However, there has been limited research attention, especially qualitative studies,…

other 2025
doi:10.1136/bmjopen-2024-087122 ·PMID:39832979

OBJECTIVES: Uterine adenomyosis is a common gynaecological disease that can be debilitating. It is poorly understood and may be overlooked in clinical settings. A research gap exists as there are currently no published scoping reviews on pe…

other 2025
doi:10.1136/bmjopen-2024-091813 ·PMID:39843375

INTRODUCTION: Early pregnancy care involves the screening and identification of women with risk factors for adverse pregnancy outcomes, including stillbirth or preterm birth, to tailor pregnancy care and interventions accordingly. Most stil…

other 2024
doi:10.1136/bmjopen-2023-081971 ·PMID:38740508

IntroductionGastrointestinal hospitalisations in the USA cause over US$130 billion in expenditures, and acute pancreatitis is a leading cause of these hospitalisations. Adequate pain control is one of the primary treatment goals for acute p…

rct 2024
doi:10.1136/bmjopen-2024-087431 ·PMID:39384241

OBJECTIVE: Pregnant women with COVID-19 are at elevated risk for severe outcomes, but clinical data on management of these patients are limited. Monoclonal antibodies, such as casirivimab plus imdevimab (CAS+IMD), have proven effective in t…

meta-analysis 2024
doi:10.1136/bmjopen-2024-088568 ·PMID:39532370

OBJECTIVES: This systematic review aims to identify, appraise and synthesise the findings of published qualitative research exploring the barriers and facilitators to self-management of chronic conditions reported by women. DESIGN: A syste…

other 2024
doi:10.1136/bmjopen-2023-074478 ·PMID:38199630

INTRODUCTION: Hysterectomy is the most common surgical procedure in the field of gynaecology. The traditional multiport laparoscopy, transumbilical laparoendoscopic single-site surgery (TU-LESS) and transvaginal natural orifice transluminal…

rct 2024
doi:10.1136/bmjopen-2024-088072 ·PMID:39653562

OBJECTIVES: To evaluate the cost-effectiveness of long-acting progestogens (LAP), including levonorgestrel-releasing intrauterine system (LNG-IUS) and depot-medroxyprogesterone acetate (DMPA), compared with the combined oral contraceptives …

other 2024
doi:10.1136/bmjopen-2024-091378 ·PMID:39414291

INTRODUCTION: Reproductive hormone transitions (menstrual cycle, post partum and menopause) can trigger mental disorders in a subset of women. Gynaecological diseases, such as endometriosis and polycystic ovary syndrome, can also elevate th…

other 2024
doi:10.1136/bmjopen-2023-079715 ·PMID:39153788

OBJECTIVE: This paper uses health economics methods to discuss the cost-effectiveness value of long protocol and antagonist protocol for in vitro fertilisation and embryo transfer (ET) in the Chinese population. DESIGN: Health economic eva…

meta-analysis 2024
doi:10.1136/bmjopen-2023-077025 ·PMID:39025820

OBJECTIVES: Pregnancy outcomes of different ovarian stimulation protocols for in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) in patients with adenomyosis are not explicit. This meta-analysis aimed to systematically evalu…

observational 2024
doi:10.1136/bmjopen-2023-074488 ·PMID:38216177

OBJECTIVES: We aimed to explore the epidemiological characteristics of suspected adenomyosis within a physical examination population in China. DESIGN: A retrospective, nested case-control study; we matched healthy people and those with po…

other 2024
doi:10.1136/bmjopen-2024-085459 ·PMID:39645251

INTRODUCTION: People with intellectual disabilities experience health inequalities at a greater level than their non-disabled peers. Notably, while general health status is starting to receive some attention, the reproductive health and rig…

other 2024
doi:10.1136/bmjopen-2023-078989 ·PMID:38216200

INTRODUCTION: Uterine fibroids affect 30%-77% of reproductive-age women and are a significant cause of infertility. Surgical myomectomies can restore fertility, but they often have limited and temporary benefits, with postoperative complica…

other 2024
doi:10.1136/bmjopen-2023-080989 ·PMID:38684268

INTRODUCTION: Endometriosis is a prevalent gynaecological condition for women of reproductive age worldwide. While endometriosis primarily involves the reproductive system, it can also infiltrate additional viscera such as the gastrointesti…

other 2024
doi:10.1136/bmjopen-2024-091549 ·PMID:39521471

INTRODUCTION: Gender is a well-established social determinant of health and health (in)equality. Gender-sensitive health indicators for health monitoring and health reporting can support gender mainstreaming in relevant policy areas and inf…

observational 2024
doi:10.1136/bmjopen-2024-085204 ·PMID:39242168

ObjectivesThis study aims to determine whether machine learning can identify specific combinations of long-term conditions (LTC) associated with increased sarcopenia risk and hence address an important evidence gap-people with multiple LTC …

other 2024
doi:10.1136/bmjopen-2024-092011 ·PMID:39645254

BACKGROUND: The global increase in caesarean sections (CS), currently at 21.1% of all deliveries, has led to a rise in uterine scar defects, or 'niches', at the hysterotomy site. These niches, detectable in 13%-84% of cases via transvaginal…

other 2024
doi:10.1136/bmjopen-2024-090402 ·PMID:39632118

BACKGROUND: Mifepristone is a selective progesterone receptor modulator with decades of data demonstrating its potential as a highly effective emergency as well as non-emergency contraceptive. Despite considerable evidence pointing to the p…

2024
doi:10.1136/bmjopen-2023-081505 ·PMID:38514147

IntroductionTreatment for abdominal pain in patients with chronic pancreatitis (CP) remains challenging in the setting of central nervous system sensitisation, a phenomenon of remodelling and neuronal hyperexcitability resulting from persis…

other 2024
doi:10.1136/bmjopen-2024-088343 ·PMID:39675827

INTRODUCTION: Autism is a lifelong minority neurotype present from birth. There is a dearth of credible evidence to suggest gender variation in Autism prevalence, despite historical under-diagnosis of women. Autistic people Assigned Female …

observational 2024
doi:10.1136/bmjopen-2024-086052 ·PMID:39477265

OBJECTIVES: This study aimed to assess the prevalence and associated risk factors of primary dysmenorrhoea among medical students in Indonesia. DESIGN: A web-based survey was conducted among 630 medical students across Indonesia, selected …

qualitative 2024
doi:10.1136/bmjopen-2023-076035 ·PMID:38553063

ObjectiveTo explore the experiences of patients with ectopic pregnancies with delayed medical care, with the goals to promote timely access to care, reduce subsequent physical and psychological impacts, and provide recommendations for impro…

other 2024
doi:10.1136/bmjopen-2024-085622 ·PMID:39182930

INTRODUCTION: Evidence suggests that when adjusted for age and other factors such as Body Mass Index, age of first pregnancy, years since last pregnancy and alcohol consumption, Black women are three times more likely to suffer from fibroid…