BMJ open

BMJ Open · ISSN (e) 2044-6055 · 292 papers in corpus
other 2024
doi:10.1136/bmjopen-2023-081979 ·PMID:38658010

INTRODUCTION: Hysterectomy is one of the most common surgeries performed in women. Minimally invasive methods are on the rise globally as they have been shown to decrease surgical morbidity compared with abdominal hysterectomy. Hysterectomy…

qualitative 2024
doi:10.1136/bmjopen-2024-087602 ·PMID:39532367

OBJECTIVES: To explore the barriers and facilitators to help-seeking behaviour for symptoms among patients with ovarian cancer in China. DESIGN: This semistructured interview-based study used a descriptive phenomenological research method.…

other 2024
doi:10.1136/bmjopen-2023-075316 ·PMID:38238180

INTRODUCTION: Uterine adenomyosis is a benign gynaecological disease that causes physical and psychological problems, impacting on relationships. It is poorly understood and consequently may be diagnosed late. This protocol describes the pr…

other 2023
doi:10.1136/bmjopen-2023-073691 ·PMID:37678943

INTRODUCTION: Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) has already proven its non-inferiority to conventional abdominal laparoscopy (CAL) for hysterectomy without conversion. The results in terms of efficacy and…

observational 2023
doi:10.1136/bmjopen-2022-070830 ·PMID:37080618

OBJECTIVE: To examine the association between hysterectomy and hypertension among middle-aged and older women in India, as well as to determine if the association differs across different age groups. DESIGN: A cross-sectional exploratory s…

observational 2023
doi:10.1136/bmjopen-2023-078167 ·PMID:38000828

OBJECTIVES: Women with a history of preterm delivery (PTD) are at higher risk of developing cardiovascular diseases (CVD) later in life. However, it is not well established whether PTD is associated with CVD risk factors, hypertension and t…

observational 2023
doi:10.1136/bmjopen-2023-072249 ·PMID:37730406

OBJECTIVES: To systematically assess the associations between various immune-mediated diseases (IMDs) and human papillomavirus (HPV)-associated diseases. DESIGN: Retrospective cohort study. SETTING: UK Biobank. PARTICIPANTS: A total of 5…

observational 2023
doi:10.1136/bmjopen-2022-066022 ·PMID:37316316

OBJECTIVES: Ovarian cancer symptoms are often non-specific and can be normalised before patients seek medical help. The Cancer Loyalty Card Study investigated self-management behaviours of patients with ovarian cancer prior to their diagnos…

observational 2023
doi:10.1136/bmjopen-2022-071137 ·PMID:38070891

ObjectivesThe aim of this multicentre COVID-PREDICT study (a nationwide observational cohort study that aims to better understand clinical course of COVID-19 and to predict which COVID-19 patients should receive which treatment and which ty…

observational 2023
doi:10.1136/bmjopen-2023-077185 ·PMID:38159963

OBJECTIVES: The Health & Her app provides menopausal women with a means of monitoring their symptoms, symptom triggers and menstrual periods, and enables them to engage in a variety of digital activities designed to promote well-being. This…

other 2023
doi:10.1136/bmjopen-2022-067497 ·PMID:36599637

INTRODUCTION: Overall, 20%-30% of women with endometriosis report endometriosis-related disability after successful laparoscopy. This indicates a potential impact of psychological factors, such as expectations, on treatment outcomes. It is …

other 2023
doi:10.1136/bmjopen-2023-076390 ·PMID:37844983

BACKGROUND: Uterine contractions may interfere with embryo implantation in assisted reproductive technology. To reduce these contractions and improve success rates, the oxytocin antagonist atosiban has been suggested for administration duri…

other 2023
doi:10.1136/bmjopen-2022-070950 ·PMID:37451732

INTRODUCTION: A uterine niche is a defect at the site of the uterine caesarean scar that is associated with gynaecological symptoms and infertility. Promising results are reported in cohort studies after a laparoscopic niche resection conce…

other 2023
doi:10.1136/bmjopen-2022-069840 ·PMID:37558441

INTRODUCTION: Women characterised by diminished ovarian reserve are considered to have poor ovarian response (POR) according to Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number (POSEIDON) criteria. Patients in this popu…

other 2023
doi:10.1136/bmjopen-2021-060483 ·PMID:36882256

INTRODUCTION: Vitamin D is associated with many functions of the human reproductive system. Accordingly, it seems that on infertile couples undergoing assisted reproduction technology (ART), treatment outcomes may be affected by the vitamin…

other 2023
doi:10.1136/bmjopen-2022-068919 ·PMID:37433731

INTRODUCTION: Current research aimed at understanding and preventing stillbirth focuses almost exclusively on the role of the placenta. The underlying origins of poor placental function leading to stillbirth, however, remain poorly understo…

other 2023
doi:10.1136/bmjopen-2023-074259 ·PMID:37620261

INTRODUCTION: The need of a regional healthcare monitoring in order to evaluate quality and utilisation of health services in smaller scale is internationally and in Germany well established. Little is known about variation in healthcare in…

other 2023
doi:10.1136/bmjopen-2022-069984 ·PMID:36787972

INTRODUCTION: Dysmenorrhoea affects up to 70%-91% of adolescents who menstruate, with approximately one-third experiencing severe symptoms with impacts on education, work and leisure. Dysmenorrhoea can occur without identifiable pathology, …

nonrandomized-trial 2023
doi:10.1136/bmjopen-2023-073517 ·PMID:38070921

IMPORTANCE: The study summarises the selection prescreen criteria currently used in the UK for a uterus transplant and highlights the number of women who are suitable to proceed. OBJECTIVES: To assess the demographics, motivations, reasons…

other 2023
doi:10.1136/bmjopen-2022-070218 ·PMID:37669836

INTRODUCTION: There is uncertainty about the advantages and disadvantages of laparoscopic hysterectomy compared with abdominal hysterectomy, particularly the relative rate of complications of the two procedures. While uptake of laparoscopic…

other 2023
doi:10.1136/bmjopen-2023-072021 ·PMID:37591656

INTRODUCTION: Hormone replacement treatment (HRT) is the most commonly used endometrial preparation protocol for frozen embryo transfer (FET) in patients with polycystic ovary syndrome (PCOS). However, studies have found that HRT may increa…

other 2023
doi:10.1136/bmjopen-2022-068718 ·PMID:36828655

INTRODUCTION: One in five pregnant women has multiple pre-existing long-term conditions in the UK. Studies have shown that maternal multiple long-term conditions are associated with adverse outcomes. This observational study aims to compare…

qualitative 2023
doi:10.1136/bmjopen-2022-063637 ·PMID:37460266

OBJECTIVE: This work contributed to the development of a core outcome set (COS) for heavy menstrual bleeding (HMB). The objective was to determine which research outcomes best reflect how HMB affects women's lives and to identify additional…

other 2023
doi:10.1136/bmjopen-2022-071246 ·PMID:37666548

INTRODUCTION: Salpingectomy is currently suggested as an alternative to tubal ligation for sterilisation. Precursor lesions of ovarian carcinoma can be found in the fallopian tubes; thus, salpingectomy could possibly reduce the incidence. M…

rct 2023
doi:10.1136/bmjopen-2022-063188 ·PMID:37479520

OBJECTIVE: The substitution of an in-study control population with a historical control (HC) population is considered a viable option for reducing the necessary recruitment of control patients. However, it is necessary to evaluate whether t…