Coon JS

No ORCID on file · 2 papers in corpus · active 2014

Study types

  • article 1

Condition tags

  • endometriosis 1
article 2014
ERβ- and Prostaglandin E2-Regulated Pathways Integrate Cell Proliferation via Ras-like and Estrogen-Regulated Growth Inhibitor in Endometriosis
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2013-1421

In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…

2014
Fenretinide: a novel treatment for endometrial cancer.
PloS one ·doi:10.1371/journal.pone.0110410

Resistance to progestin treatment is a major hurdle in the treatment of advanced and reoccurring endometrial cancer. Fenretinide is a synthetic retinoid that has been evaluated in clinical trials as a cancer therapeutic and chemo-preventive…