Matthew T. Dyson

ORCID: 0000-0003-3596-5753 · 22 papers in corpus · active 2011-2018

Study types

  • article 16
  • other 3
  • review 2
  • letter 1

Condition tags

  • endometriosis 22
  • infertility 5
  • chronic_pelvic_pain 1
other 2018
Stem cell reports ·doi:10.1016/j.stemcr.2018.10.002

Defective endometrial stromal fibroblasts (EMSFs) contribute to uterine factor infertility, endometriosis, and endometrial cancer. Induced pluripotent stem cells (iPSCs) derived from skin or bone marrow biopsies provide a patient-specific s…

article 2018
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118756751
article 2017
Reproduction (Cambridge, England) ·doi:10.1530/rep-16-0592

Decidualization alters multiple molecular pathways in endometrium to permit successful embryo implantation. We have reported that paracrine factors, including retinoids, secreted from progesterone-treated endometrial stromal cells, act on n…

other 2016
Fertility and sterility ·doi:10.1016/j.fertnstert.2016.01.012

OBJECTIVE: To determine the expression and biological roles of serum and glucocorticoid-regulated kinase (SGK1) in tissues and cells from patients with endometriosis and from healthy control subjects. DESIGN: Case-control. SETTING: Univer…

article 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116632920
article 2016

Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…

article 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.06.046
review 2015
Seminars in reproductive medicine ·doi:10.1055/s-0035-1554053

Endometriosis has been initially described as the presence of ectopic endometrial tissue on pelvic organs or in extrapelvic sites; and this has been used as its key pathologic feature ever since. Endometriosis responds to fluctuations in es…

article 2015
·doi:10.1016/j.fertnstert.2015.07.212
article 2014
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2013-1421

In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…

article 2014
·doi:10.1016/j.fertnstert.2014.07.044
article 2014
PLoS genetics ·doi:10.1371/journal.pgen.1004158

Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…

other 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.03.030

OBJECTIVE: To define altered gene expression networks in endometriosis. DESIGN: Experiments using endometriotic tissues and primary cells. SETTING: Division of Reproductive Biology Research, Northwestern University. PATIENT(S): Premenopa…

letter 2012
Nature medicine ·doi:10.1038/nm.2855
article 2012
·doi:10.1016/j.fertnstert.2012.07.334
article 2012
·doi:10.1093/biolreprod/87.s1.321

Endometriosis is an estrogen-dependent gynecological disease that affects 6–10% of women of reproductive age. It is a major cause of chronic pelvic pain and infertility, and poses a heavy financial burden on society, with annual estimates t…

article 2012
·doi:10.1016/j.fertnstert.2012.07.241
article 2012
·doi:10.1093/biolreprod/87.s1.280

Endometriosis is a benign gynecological disease causing infertility, adhesions and chronic pain in approximately 10% of reproductively-aged women due to the extrauterine growth of endometrial stromal and glandular cells. Endometriotic lesio…

review 2012
Seminars in reproductive medicine ·doi:10.1055/s-0031-1299596

Endometriosis is an estrogen-dependent disease. The biologically active estrogen, estradiol, aggravates the pathological processes (e.g., inflammation and growth) and the symptoms (e.g., pain) associated with endometriosis. Abundant quantit…

article 2011
·doi:10.1016/j.fertnstert.2011.07.531
article 2011
·doi:10.1016/j.fertnstert.2011.07.379
article 2011
Human Reproduction ·doi:10.1093/humrep/der172

BACKGROUND: Retinoic acid (RA) regulates key biological processes, including differentiation, apoptosis and cell survival. RA mediates induction of 17 beta-hydroxysteroid dehydrogenase type 2 mRNA, catalyzing the conversion of estradiol to …