Masanori Ono

ORCID: 0000-0001-9249-6813 · 13 papers in corpus · active 2005-2025

Study types

  • article 7
  • review 4
  • other 2

Condition tags

  • endometriosis 11
  • infertility 2
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
  • dyspareunia 1
other 2025
Molecular reproduction and development ·doi:10.1002/mrd.70046

Endometriosis is hypothesized to result from retrograde menstruation where cell debris including endometrial stromal cells (ESCs) travel through the fallopian tubes. This chronic inflammatory disease is characterized by inflammatory and fib…

other 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.966455

Endometriosis is characterized by the presence of inflamed and fibrotic endometrial tissue outside the uterine cavity. Previously, we found decreased SERPINA1 (alpha-1 antitrypsin) expression in endometriosis-like lesions in a mouse model o…

article 2016

Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…

article 2015
Fertility and sterility ·doi:10.1016/j.fertnstert.2015.06.046
article 2014
Molecular endocrinology (Baltimore, Md.) ·doi:10.1210/me.2013-1421

In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…

article 2014
PLoS genetics ·doi:10.1371/journal.pgen.1004158

Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…

article 2013
Endocrine journal ·doi:10.1507/endocrj.ej13-0027

Nerve growth factor (NGF) has been recently proposed as one of the key factors responsible not only for promotion of nerve fiber growth but also for the onset and maintenance of pain in a variety of diseases. The aim of this study was to in…

review 2013
·doi:10.1016/j.placenta.2012.12.010
review 2010
Reproduction (Cambridge, England) ·doi:10.1530/rep-09-0438

The human uterus mainly consists of the endometrium and the outer smooth muscle layer termed the myometrium. The uterus harbours the exceptional and remarkable regenerative ability responsible for cyclical regeneration and remodelling throu…

article 2010
PloS one ·doi:10.1371/journal.pone.0010387

BACKGROUND: The human endometrium undergoes cyclical regeneration throughout a woman's reproductive life. Ectopic implantation of endometrial cells through retrograde menstruation gives rise to endometriotic lesions which affect approximate…

review 2008
·doi:10.2147/sccaa.s4269

Regeneration and adult stem cells in the human female reproductive tract Masanori Ono, Tetsuo Maruyama, Yasunori YoshimuraDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku, Tokyo, JapanAbstract: The human…

article 2007
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.0604310104

Human uterine endometrium exhibits unique properties of cyclical regeneration and remodeling throughout reproductive life and also is subject to endometriosis through ectopic implantation of retrogradely shed endometrial fragments during me…

review 2005
Reproductive medicine and biology ·doi:10.1111/j.1447-0578.2005.00101.x

Acetylation of histones is cooperatively regulated by two groups of enzymes, histone acetyltransferases and histone deacetylases. Histone acetylation status plays a fundamental role in the level of gene transcription; numerous studies have …