Nozawa S

No ORCID on file · 20 papers in corpus · active 1990-2007

Study types

  • article 15
  • other 5

Condition tags

  • endometriosis 19
article 2007
The Journal of reproductive medicine

OBJECTIVE: To investigate the factors related to activation of transforming growth factor-beta 1 (TGF-beta1) at sites of endometriosis. STUDY DESIGN: TGF-beta1 is activated by plasmin, which is formed when plasminogen is activated by urokin…

other 2006
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2005.11.030

OBJECTIVE: To investigate differences in the biological characteristics of ovarian clear cell adenocarcinoma based on the presence/absence of endometriosis and tumor proliferative activity. METHODS: Stage I ovarian clear cell adenocarcinom…

article 2005
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1111/j.1048-891x.2005.15004.x

A new efficient screening for ovarian cancer based on a combination of two tumor markers, CA602 and CA546, is reported. These two tumor markers can be detected by a combination immunoenzymometric assay of these two antigens. This combinatio…

article 2005
Journal of bone and mineral metabolism ·doi:10.1007/s00774-005-0618-3

Our objective was to assess the effects of 6 months' treatment with two types of gonadotropin-releasing hormone (GnRH) analogues on lumbar bone mineral density (BMD) and bone metabolism. We studied 27 women who had been given a diagnosis of…

article 2001
Nihon rinsho. Japanese journal of clinical medicine
article 1999
Gynecologic oncology ·doi:10.1006/gyno.1998.5284

ObjectiveOvarian clear cell carcinoma is commonly associated with pelvic endometriosis. We retrospectively evaluated clinicopathological data on the association between ovarian clear cell carcinoma and pelvic endometriosis.MethodsBetween 19…

article 1998
European journal of cancer (Oxford, England : 1990) ·doi:10.1016/s0959-8049(97)10079-x

In this study clinical studies were conducted on galactosyltransferase associated with tumour (GAT) as a newly developed marker of ovarian cancers. The positive rates of GAT with a cut-off value of 16 U/ml (which corresponds to the mean + 2…

article 1998
European journal of endocrinology ·doi:10.1530/eje.0.1380216

OBJECTIVE: Dienogest, a synthetic steroid with progestational activity, is used as a component of oral contraceptives and is currently being evaluated clinically for the treatment of endometriosis. The present study was conducted to confirm…

article 1997
Drugs under experimental and clinical research

Dienogest is an orally active synthetic steroid that is used for contraception and is currently being studied for the possible treatment of endometriosis. Earlier we demonstrated that dienogest had therapeutic effects on experimental endome…

article 1997
Cancer ·doi:10.1002/(sici)1097-0142(19970101)79:1<169::aid-cncr24>3.0.co;2-1

BACKGROUND: Dienogest is a synthetic progestational steroid that is used for contraception. It is being studied for the treatment of endometriosis, but its anticancer activity remains unknown. The authors investigated the anticancer effect …

article 1995
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1995.tb00899.x

PROBLEM: This study examines immune cell populations in rats with autotransplanted endometrium and determines the effect of danazol on leukocyte subsets. METHODS: As an experimental model of endometriosis, an autologous endometrial segment …

article 1994
Gan to kagaku ryoho. Cancer & chemotherapy

We examined GAT, a newly developed tumor marker, in serum samples collected from 1,503 females in six institutions: 387 healthy females, 1,052 patients with gynecological diseases including 311 ovarian cancers, and 64 with nongynecological …

article 1994
Gan to kagaku ryoho. Cancer & chemotherapy

Serum samples from patients with benign or malignant diseases were measured for the newly developed tumor markers CA54/61 and CA602 with the respective EIA kits for assessment of their utility as tumor markers. A total of 5236 patients were…

other 1993
Rinsho byori. The Japanese journal of clinical pathology
article 1993
International journal of fertility and menopausal studies

OBJECTIVE: To evaluate cell-mediated immunity in endometriosis. DESIGN: Peritoneal fluid and peripheral blood samples from 19 women with macroscopic evidence of endometriosis and 26 controls were submitted to 2-color flow cytometric analysi…

article 1993
Gan to kagaku ryoho. Cancer & chemotherapy

Galactosyltransferase Associated with Tumor (GAT) was clinically studied in cases of ovarian cancer. When two cut-off levels of GAT were compared, the cut-off level of 16 U/ml (which corresponds to mean + 2SD among healthy females) was foun…

other 1992
Nihon rinsho. Japanese journal of clinical medicine

Tumor DNA content (ploidy) was determined by flow-cytometry (FCM) on tissue from 32 epithelial ovarian cancer patients. Staining for DNA analysis was achieved with Propidium Iodide. Peripheral blood lymphocytes were used as reference diploi…

other 1991
Japanese journal of cancer research : Gann ·doi:10.1111/j.1349-7006.1991.tb02713.x

A cell line designated RMG-II was established from the ascites of a patient with ovarian clear cell carcinoma. The chromosomal analysis revealed aneuploidy with a hypertetraploid modal number and 8 marker chromosomes. Radioimmunoassay and i…

other 1991
Nihon Sanka Fujinka Gakkai zasshi

The DNA content in individual cells from 40 cases of histopathologically normal endometria, 15 of endometrial hyperplasia and 68 of endometrial adenocarcinoma was measured by flow cytometry. An aneuploid cell population was found in 50% of …

article 1990
Nihon Sanka Fujinka Gakkai zasshi

Danazol, which is commonly employed in the treatment of endometriosis creates a low estrogen and high androgen condition by suppressing ovarian steroidogenesis. When a reproductive-aged woman suddenly develops low estrogen, even if it is re…