The purpose of this study was to clarify the relationship between NK activity and TG-beta in the immune system in endometriosis. We investigated (1) the changes in the NK activity and concentration of TGF-beta in human peritoneal fluid (HPF…
The etiology and the pathogenesis of adenomyosis, which is a benign disease featuring ectopic proliferation and invasion of the endometrial stromas and glands into the myometrium, as seen with malignant tumor cells, are still unknown. Adeno…
UNLABELLED: We examined the effect of experimental endometriosis (EE) on natural killer (NK) activities and fertilizability in the rat. EE was induced by autotransplantation of an endometrial fragment to the peritoneal wall. As a sham, abdo…
It is difficult to distinguish a small endometrial implant from adipose tissue by magnetic resonance imaging (MRI). I assessed the usefulness of fat saturated MRI in detecting small endometrial implants by comparing it with conventional MRI…
A total of 260 unfertilized human oocytes obtained in our IVF program were studied cytogenetically, by a gradual fixation-air drying method proposed by Mikamo and Kamiguchi (1983). The oocytes were obtained from 72 cycles of 52 patients (me…
The etiology and the pathogenesis of adenomyosis, which is a benign uterine disease featuring the ectopic proliferation of endometrial tissues and glands into the myometrium and the serosa in the uterus, are still unknown. A novel mouse str…
To investigate the pathogenesis of peritoneal endometriosis, the morphology of peritoneal endometriosis was studied by scanning electron microscopy (SEM) and light microscopy (LM). After taking biopsies from peritoneal lesions which were su…
Assisted hatching (AHA) techniques were used in 67 patients who had repeatedly failed to achieve conception by conventional IVF-ET in spite of replacement by good quality embryos. The age of the female patients ranged from 28 to 44 years an…
UNLABELLED: CA125 has been regarded as a marker for hyperplastic conditions, such as endometriosis or infectious peritonitis. A high serum CA125 level should therefore be carefully evaluated clinically. We measured CA125 levels in sera and …
Twenty-one human ovarian epithelial carcinomas (13 serous, 3 mucinous, 2 endometrioid and 3 clear cell type) were examined for allelic losses of p53 tumor suppressor gene, pYNZ22 or pTHH59 on chromosome 17. High-molecular-weight DNA was ext…
The purpose of this study was to assess whether endometriotic implants of endometriosis could produce Interleukin (IL)-6. IL-6 was measured by means of an enzyme-linked immunosorbent assay (ELISA) in 21 patients with endometriosis of stage …
In order to study the effect of peritoneal macrophages (M phi) on conception in patients with endometriosis, the total numbers of peritoneal M phi and the proportion of the exudate type, defined on the basis of ultracytochemical localizatio…
To assess bone metabolism during treatment with gonadotropin-releasing hormone analogue (GnRHa), serum osteocalcin (BGP), alkaline phosphatase (ALP), parathyroid hormone (PTH), calcitonin (CT), calcium (Ca) and phosphorus (P) were determine…