Study types
- article 3
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- meta-analysis 1
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Condition tags
- endometriosis 9
- infertility 1
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Frequent coauthors
- Madelon van Wely 13
- Fulco van der Veen 10
- Bossuyt PM 7
- Ben W J Mol 7
- Mol BW 7
- Verhoeve HR 6
- Eijkemans MJ 5
- Repping S 5
- Hoek A 4
- Mochtar MH 4
Study questionIs IVF with frozen-thawed blastocyst transfer (freeze-all strategy) more effective than IVF with fresh and frozen-thawed blastocyst transfer (conventional strategy)?Summary answerThe freeze-all strategy was inferior to the con…
BackgroundClinical management for unexplained infertility includes expectant management as well as active treatments, including ovarian stimulation (OS), intrauterine insemination (IUI), OS-IUI, and in vitro fertilisation (IVF) with or wit…
STUDY QUESTION: Which couples with unexplained subfertility can expect increased chances of ongoing pregnancy with IVF compared to expectant management? SUMMARY ANSWER: For couples in which the woman is under 40 years of age, IVF is associa…
STUDY QUESTION: How well does a previously developed dynamic prediction model perform in an external, geographical validation in terms of predicting the chances of natural conception at various points in time? SUMMARY ANSWER: The dynamic pr…
BackgroundThe first-line treatment in donor sperm treatment consists of inseminations that can be done by intrauterine insemination (IUI) or by intracervical insemination (ICI).ObjectivesTo compare the effectiveness and safety of intrauteri…
BACKGROUND: Tubal pathology is a causative factor in 20% of subfertile couples. Traditionally, tubal testing during fertility work-up is performed by hysterosalpingography (HSG). Hysterosalpingo-foam sonography (HyFoSy) is a new technique t…
BackgroundOne of the various ovarian stimulation regimens used for in-vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) cycles is the use of recombinant follicle-stimulating hormone (rFSH) in combination with a gonadotrop…
ObjectivesTo compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a…
BackgroundHuman chorionic gonadotropin (HCG) is routinely used for final oocyte maturation triggering in in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) cycles, but the use of HCG for this purpose may have drawbacks. Go…
Since the introduction of in vitro fertilization (IVF) in 1978, over five million babies have been born worldwide using IVF. Contrary to the perception of many, IVF does not guarantee success. Almost 50% of couples that start IVF will remai…
STUDY QUESTION: What reproductive choices do women make after they have cryopreserved oocytes for medical reasons? SUMMARY ANSWER: Women who had cryopreserved oocytes for medical reasons and tried to become pregnant, either attempted natur…
STUDY QUESTION: Are we able to develop a model to calculate the chances of pregnancy prior to the start of the first IVF cycle as well as after one or more failed cycles? SUMMARY ANSWER: Our prediction model enables the accurate individual…
BackgroundLong-term effects of ovarian stimulation for IVF on the risk of ovarian malignancies are unknown.MethodsWe identified a nationwide historic cohort of 19,146 women who received IVF treatment in the Netherlands between 1983 and 1995…
BACKGROUND: In the Netherlands, 30% of subfertile women are overweight or obese, and at present there is no agreement on fertility care for them. Data from observational and small intervention studies suggest that reduction of weight will i…
BACKGROUND: Multiple pregnancies are high risk pregnancies with higher chances of maternal and neonatal mortality and morbidity. In the past decades the number of multiple pregnancies has increased. This trend is partly due to the fact that…
BACKGROUND: Guidelines recommend diagnostic laparoscopy in subfertile women with known co-morbidities in their medical history. Aggregated evidence underpinning these recommendations is, however, currently lacking. OBJECTIVE: The objective…
BackgroundFor most tubal ectopic pregnancies (EP) surgery is the treatment of first choice. Whether surgical treatment should be performed conservatively (salpingostomy) or radically (salpingectomy) in women wishing to preserve their reprod…
ObjectiveTo develop a prognostic model for the outcome of IUI.DesignRetrospective cohort study.SettingFour fertility centers in The Netherlands.Patient(s)Couples of whom the female partners had a regular cycle and who had been treated with …
ObjectiveTo compare the effectiveness of an electrocautery strategy with ovulation induction using recombinant follicle stimulating hormone in patients with polycystic ovary syndrome.DesignRandomised controlled trial.SettingSecondary and te…
ObjectiveTo assess the diagnostic performance of serum CA-125 measurement in the detection of endometriosis.DesignMeta-analysis.Setting and patient(s)Twenty-three studies comparing serum CA-125 levels and laparoscopically confirmed endometr…