The Cochrane database of systematic reviews

Cochrane Database Syst Rev · ISSN (e) 1469-493X · 82 papers in corpus
meta-analysis 2026
doi:10.1002/14651858.CD014968.pub2 ·PMID:42081299

BACKGROUND: Around 18% to 33% of couples with infertility present with tubal occlusion (blocked or damaged fallopian tubes) or hydrosalpinx (fluid-filled tubes). Diagnostic laparoscopy (keyhole surgery) with chromopertubation (methylene blu…

article 2025
doi:10.1002/14651858.cd002122.pub3 ·PMID:41065045

BACKGROUND: Endometriosis is a hormone-sensitive inflammatory condition affecting between 5% and 10% of reproductive-aged women and an unknown number of gender-diverse individuals. It is often associated with debilitating pelvic pain sympto…

other 2024
doi:10.1002/14651858.CD004992.pub4 ·PMID:39588841

BACKGROUND: Endometrioma are endometriotic deposits within the ovary. Laparoscopic management of endometriomas is associated with shorter hospital stay, faster recovery, and decreased hospital costs compared with laparotomy. The previous ve…

review 2023
doi:10.1002/14651858.cd014788.pub2 ·PMID:37341141

BACKGROUND: Endometriosis is a common gynaecological condition affecting 6 to 11% of reproductive-age women and may cause dyspareunia, dysmenorrhoea, and infertility. One treatment strategy is medical therapy with gonadotrophin-releasing ho…

other 2023
doi:10.1002/14651858.CD003677.pub6 ·PMID:37642285

BACKGROUND: Currently, there are five major approaches to hysterectomy for benign gynaecological disease: abdominal hysterectomy (AH), vaginal hysterectomy (VH), laparoscopic hysterectomy (LH), robotic-assisted hysterectomy (RH) and vaginal…

other 2021
doi:10.1002/14651858.CD005356.pub3 ·PMID:34739136

BACKGROUND: Intrauterine insemination (IUI), combined with ovarian stimulation (OS), has been demonstrated to be an effective treatment for infertile couples. Several agents for ovarian stimulation, combined with IUI, have been proposed, bu…

article 2021
doi:10.1002/14651858.cd005072.pub4 ·PMID:34928503

BACKGROUND: Endometriosis is a condition characterised by the presence of ectopic deposits of endometrial-like tissue outside the uterus, usually in the pelvis. The impact of laparoscopic treatment on overall pain is uncertain and a signifi…

review 2021
doi:10.1002/14651858.cd007677.pub4 ·PMID:34431079

BACKGROUND: Endometriosis is a chronic inflammatory condition that occurs during the reproductive years. It is characterised by endometrium-like tissue developing outside the uterine cavity. This endometriotic tissue development is dependen…

review 2021
doi:10.1002/14651858.cd011169.pub2 ·PMID:33973648

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. This chronic and recurring condition occurs in women of reproductive age. It is a common cause of pain or infertility and can cause non-s…

other 2021
doi:10.1002/14651858.CD008212.pub2 ·PMID:34923620

BACKGROUND: Chronic pelvic pain (CPP) is a common gynaecological condition accounting for 20% of all gynaecological referrals. There are wide ranges of causes with overlapping symptomatology, therefore the management of the condition is a f…

meta-analysis 2020
doi:10.1002/14651858.CD000475.pub4 ·PMID:32199406

BACKGROUND: Pelvic adhesions can form secondary to inflammation, endometriosis, or surgical trauma. Strategies to reduce pelvic adhesion formation include placing barrier agents such as oxidised regenerated cellulose, polytetrafluoroethylen…

meta-analysis 2020
doi:10.1002/14651858.CD001298.pub5 ·PMID:32683695

BACKGROUND: Adhesions are fibrin bands that are a common consequence of gynaecological surgery. They are caused by conditions that include pelvic inflammatory disease and endometriosis. Adhesions are associated with comorbidities, including…

meta-analysis 2020
doi:10.1002/14651858.CD013352.pub2 ·PMID:32374421

BACKGROUND: Uterine leiomyomas, also referred to as myomas or fibroids, are benign tumours arising from the smooth muscle cells of the myometrium. They are the most common pelvic tumour in women. The estimated rate of leiomyosarcoma, found …

meta-analysis 2020
doi:10.1002/14651858.CD011031.pub3 ·PMID:33095458

BACKGROUND: Endometriosis is associated with pain and infertility. Surgical interventions aim to remove visible areas of endometriosis and restore the anatomy. OBJECTIVES: To assess the effectiveness and safety of laparoscopic surgery in t…

review 2020
doi:10.1002/14651858.cd003678.pub3 ·PMID:33206374

BACKGROUND: Endometriosis is a common gynaecological condition affecting 10% to 15% of reproductive-age women and may cause dyspareunia, dysmenorrhoea, and infertility. One treatment strategy is combining surgery and medical therapy to redu…

review 2019
doi:10.1002/14651858.cd013240.pub2 ·PMID:31747470

BACKGROUND: Endometriosis is known to have an impact on fertility and it is common for women affected by endometriosis to require fertility treatments, including in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI), to im…

other 2019
doi:10.1002/14651858.CD011422.pub2 ·PMID:30985921

BACKGROUND: This is an updated merged review of two originally separate Cochrane reviews: one on robot-assisted surgery (RAS) for benign gynaecological disease, the other on RAS for gynaecological cancer. RAS is a relatively new innovation …

review 2018
doi:10.1002/14651858.cd001019.pub3 ·PMID:29786828

BACKGROUND: Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The combined oral contraceptive pill (COCP) is widely used to treat pain occ…

review 2017
doi:10.1002/14651858.cd004753.pub4 ·PMID:28114727

BACKGROUND: Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It greatly affects women's quality of life, impacting their careers, everyday activities, sexual and nonsexu…

review 2017
doi:10.1002/14651858.cd009881.pub2 ·PMID:28742263

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antipr…

review 2016
doi:10.1002/14651858.cd012179 ·PMID:27132058

BACKGROUND: About 10% of reproductive-aged women suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surg…

review 2016
doi:10.1002/14651858.cd012281 ·PMID:27405583

BACKGROUND: About 10% of women of reproductive age suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries su…

meta-analysis 2016
doi:10.1002/14651858.CD002124.pub2 ·PMID:27000311

BACKGROUND: Dysmenorrhoea refers to painful menstrual cramps and is a common gynaecological complaint. Conventional treatments include non-steroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs), which both reduce myo…

review 2016
doi:10.1002/14651858.cd012165 ·PMID:27094925

BACKGROUND: About 10% of reproductive-aged women suffer from endometriosis, which is a costly, chronic disease that causes pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but it is expensive…

review 2016
doi:10.1002/14651858.cd009591.pub2 ·PMID:26919512

BACKGROUND: About 10% of women of reproductive age suffer from endometriosis. Endometriosis is a costly chronic disease that causes pelvic pain and subfertility. Laparoscopy, the gold standard diagnostic test for endometriosis, is expensive…