Brown MB

Study questionIs there an association between fertility status, method of conception and the risks of birth defects and childhood cancer?Summary answerThe risk of childhood cancer had two independent components: (i) method of conception and…

PurposeExcess embryos transferred (ET) (> plurality at birth) and fetal heartbeats (FHB) at 6 weeks' gestation are associated with reductions in birthweight and gestation, but prior studies have been limited by small sample sizes and limite…

Study questionWhat is the association between ART conception and treatment parameters and the risk of birth defects?Summary answerCompared to naturally conceived singleton infants, the risk of a major nonchromosomal defect among ART singlet…

BackgroundAlthough in vitro fertilization has been associated with an increased risk for hypertensive disorders of pregnancy, the association of risk with in vitro fertilization treatment parameters is unclear.ObjectiveTo evaluate risk for …

ImportanceIn vitro fertilization (IVF) is associated with birth defects and imprinting disorders. Because these conditions are associated with an increased risk of childhood cancer, many of which originate in utero, descriptions of cancers …

PurposeTo evaluate the risk of prematurity and infant mortality by maternal fertility status, and for in vitro fertilization (IVF) pregnancies, by oocyte source and embryo state combinations.MethodsWomen in 14 States who had IVF-conceived l…

BackgroundOver the past 2 decades the characteristics of women giving birth in the United States and the nature of the births themselves have changed dramatically, with increases in older maternal age, plural births, cesarean deliveries, an…

PurposeTo evaluate factors associated with interpregnancy interval (IPI) among women treated with in vitro fertilization (IVF).MethodsWomen with at least two cycles of IVF between 2004 and 2013 were identified from the SART CORS database an…

Study questionHow do the assisted reproductive technology (ART) outcomes of women presenting for ART after cancer diagnosis compare to women without cancer?Summary answerThe likelihood of a live birth after ART among women with prior cancer…

PurposeThe purpose of the present study is to estimate the proportion of women with cancer who return to use the embryos that they have banked and to compare this proportion to that of women without cancer who bank embryos.MethodsThis is a …

ObjectiveThe purpose of this study was to use a validated prediction model to examine whether single embryo transfer (SET) over 2 cycles results in live birth rates (LBR) comparable with 2 embryos transferred (DET) in 1 cycle and reduces th…

ObjectiveTo evaluate the risk of cancer after assisted reproductive technology (ART) therapy.DesignLongitudinal cohort study.SettingNot applicable.Patient(s)New York, Texas, and Illinois residents between 2004 and 2009, treated with ART, co…

OBJECTIVE: To evaluate the correlation between total gonadotropin dose and live birth rate. DESIGN: Retrospective analysis. SETTING: Not applicable. PATIENT(S): A total of 658,519 fresh autologous cycles of in vitro fertilization (IVF) r…

ObjectiveTo develop a model predictive of live-birth rates (LBR) and multiple birth rates (MBR) for an individual considering assisted reproduction technology (ART) using linked cycles from Society for Assisted Reproductive Technology Clini…

ObjectiveTo model morphological assessments of embryo quality that are predictive of live birth.DesignLongitudinal cohort using cycles reported in the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System (SART CORS)…

PURPOSE: This study uses linked cycles of assisted reproductive technology (ART) to examine cumulative live birth rates, birthweight, and length of gestation by diagnostic category. METHODS: We studied 145,660 women with 235,985 ART cycles…

ObjectiveTo evaluate the effect of a prior assisted reproductive technology (ART) live birth on subsequent live-birth rates.DesignHistorical cohort study.SettingClinic-based data.Patient(s)The study population included 297,635 women with 54…

BackgroundLive-birth rates after treatment with assisted reproductive technology have traditionally been reported on a per-cycle basis. For women receiving continued treatment, cumulative success rates are a more important measure.MethodsWe…

OBJECTIVE: To evaluate factors associated with the use of elective single embryo transfer (eSET) and its effect on assisted reproductive technology (ART) outcome. DESIGN: Historical cohort. SETTING: Clinic-based data. PATIENT(S): A total…

ObjectiveTo evaluate ethnic differences in assisted reproductive technology (ART) outcomes in the United States.DesignHistorical cohort study.SettingClinic-based data.Patient(s)A total of 139,027 ART cycles from the Society for Assisted Rep…

ObjectiveTo evaluate the risks of pregnancy complications and adverse outcomes associated with increasing maternal age and higher plurality.DesignPopulation-based, historic cohort study.SettingUS birth certificates and infant death certific…

The cervicovaginal and endometrial isolation rates of Ureaplasma urealyticum and Mycoplasma hominis and relevant demographic data were obtained at the time of laparoscopy in 193 women from infertile marriage. For comparative purposes, ferti…