Bert W O'Malley

No ORCID on file · 9 papers in corpus · active 2012-2022

Study types

  • article 4
  • other 3
  • review 2

Condition tags

  • endometriosis 9
  • infertility 3
other 2022
Journal of Biomedical Science ·doi:10.1186/s12929-022-00883-2

BACKGROUND: Endometriosis is an estrogen-dependent inflammatory reproductive disease. Therefore, systematic estrogen depletion and anti-inflammatory drugs are the current treatment for endometriosis. However, current endometriosis treatment…

article 2019
Endocrinology ·doi:10.1210/en.2019-00442

Estrogen receptor (ER) β plays a critical role in endometriosis progression because cytoplasmic ERβ stimulates proinflammatory signaling in ectopic lesions and prevents apoptosis to promote their survival. However, the role of "nuclear ERβ"…

other 2018
The Journal of endocrinology ·doi:10.1530/JOE-17-0700

The steroid receptor coactivator (SRC)-1 isoform/estrogen receptor (ER)-β axis has an essential role in endometriosis progression. In this context, therefore, bufalin was employed as a 'tool compound' to evaluate inhibitors of SRC in altern…

article 2015
Cell ·doi:10.1016/j.cell.2015.10.034
other 2015
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2015.08.012

The steroid receptor coactivators (SRCs/p160/NCOA) are a family of three transcriptional coregulators initially discovered to transactivate the transcriptional potency of steroid hormone receptors. Even though SRCs were also found to modula…

review 2015
The Journal of steroid biochemistry and molecular biology ·doi:10.1016/j.jsbmb.2015.06.010

The steroid receptor coactivators (SRCs/p160/NCOA) are a family of three transcriptional coregulators initially discovered to transactivate the transcriptional potency of steroid hormone receptors. Even though SRCs were also found to modula…

article 2015
Molecular pharmacology ·doi:10.1124/mol.115.100925
review 2014
Human reproduction update ·doi:10.1093/humupd/dmu002

BACKGROUND: Endometriosis is defined as the colonization and growth of endometrial tissue at anatomic sites outside the uterine cavity. Up to 15% of reproductive-aged women in the USA suffer from painful symptoms of endometriosis, such as i…

article 2012
Nature medicine ·doi:10.1038/nm.2826