The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety

Sang Jun Han, Khurshida Begum, Charles E Foulds, Ross A Hamilton, Suzanna Bailey, Anna Malovannaya, Doug W. Chan, Doug Chan, Jun Qin, Bert W. O’Malley, Bert W O'Malley
Molecular pharmacology · 2015 · vol. 89(1) , pp. 14–26 · doi:10.1124/mol.115.100925 · PMID:26487511 · W2183215074
article OA: bronze CC0 ⤵ 3 in-corpus citations
📄 Open PDF View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This research investigates the dual inhibitory effects of a Tissue-Selective Estrogen Receptor Alpha (SERA) modulator on both endometrial proliferation and breast cancer cell growth.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

My notes (saved in your browser only)

Condition tags

mesh:D004715

MeSH descriptors

Breast Neoplasms Endometriosis Estrogen Receptor alpha Estrogens, Conjugated (USP) Estrogens, Conjugated (USP) Animals Breast Breast Breast Breast Neoplasms Breast Neoplasms Endometriosis Endometriosis Endometrium Endometrium Endometrium Estrogen Receptor alpha Estrogen Receptor alpha Estrogens Estrogens

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (69)

Cited by (3)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:17:33.600579+00:00
License: CC0 · commercial use OK