Jun Qin

ORCID: 0000-0002-2647-9270 · 4 papers in corpus
2018
The pathogenic role of estrogen receptor beta drives in endometriosis
·doi:10.1530/endoabs.54.oc5

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

lab-animal 2015
Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis
Cell ·doi:10.1016/j.cell.2015.10.034

Alterations in estrogen-mediated cellular signaling play an essential role in the pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels, enhanced ERβ activity was detected in endometriotic tissues, and the inh…

lab-animal 2015
The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety
Molecular pharmacology ·doi:10.1124/mol.115.100925

The conjugated estrogen /: bazedoxifene tissue-selective estrogen complex (TSEC) is designed to minimize the undesirable effects of estrogen in the uterus and breast tissues and to allow the beneficial effects of estrogen in other estrogen-…

lab-animal 2012
A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis
Nature medicine ·doi:10.1038/nm.2826

Endometriosis is considered to be an estrogen-dependent inflammatory disease, but its etiology is unclear. Thus far, a mechanistic role for steroid receptor coactivators (SRCs) in the progression of endometriosis has not been elucidated. An…