Cell

Cell · ISSN (e) 1097-4172 · 5 papers in corpus
review 2021
doi:10.1016/j.cell.2021.04.041 ·PMID:34048704

Endometriosis is a common condition associated with infertility that causes chronic pain in many, but not all, women. It is defined by the presence of endometrial-like tissue outside the uterus. Although the cause and natural history of the…

review 2019
doi:10.1016/j.cell.2019.11.033 ·PMID:31951524

Endometriosis is chronic disorder with high socioeconomic impact defined by the presence of endometrial-like tissue ("lesions") outside the uterus. Genetic, hormonal, and immunological factors as well as endometrial progenitor cells are imp…

review 2017
doi:10.1016/j.cell.2017.05.015 ·PMID:28575665

Many cellular stresses activate senescence, a persistent hyporeplicative state characterized in part by expression of the p16INK4a cell-cycle inhibitor. Senescent cell production occurs throughout life and plays beneficial roles in a variet…

lab-animal 2015
doi:10.1016/j.cell.2015.10.034 ·PMID:26544941

Alterations in estrogen-mediated cellular signaling play an essential role in the pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels, enhanced ERβ activity was detected in endometriotic tissues, and the inh…

other 2012
doi:10.1016/j.cell.2012.08.024 ·PMID:22980976

We report the results of whole-genome and transcriptome sequencing of tumor and adjacent normal tissue samples from 17 patients with non-small cell lung carcinoma (NSCLC). We identified 3,726 point mutations and more than 90 indels in the c…