Hulusi Bülent Zeyneloğlu

Background: The current study tested the level of endocan, which is thought to have an effective role in both endothelial dysfunction and inflammation, in infertile women with endometriosis treated with in vitro fertilization/intracytoplasm…

Aims: To determine the effects of a tumor necrosis factor inhibitor (etanercept) on pregnancy outcomes in patients with endometrioma who were treated with assisted reproductive technology. Methods: Sixty-eight infertile patients who had end…

In this study it is aimed to define a rare case of deep pelvic endometriosis with massive serous ascites and infertility. Literature search revealed sporadic cases of endometriosis presenting with bloody or brownish ascites, some had also p…

PurposeTo assess the effects of amifostine, N-acetyl cysteine (NAC), and leuprolide as a scavenger in a rat endometriosis model.MethodsThis is a prospective randomized animal study. Setting The Animal Laboratory of Medical University. Anima…

We report 2 patients with pelvic-peritoneal tuberculosis and elevated serum and peritoneal fluid levels of Ca-125. The first was a young and infertile women who had cul-de-sac nodularity and dysmenorrhea. The other was postmenopausal and pr…

BACKGROUND: Doxycycline (Dox) has a number of non-antibiotic properties. One of them is the inhibition of matrix metalloproteinase (MMP) activity. The aim of this study was to assess the effects of Dox in a rat endometriosis model. METHODS:…

Fenofibrate -a peroxisome proliferator-activated receptor-a agonist- is an angiostatic agent that is commonly used in human liver diseases, therefore it may interfere with the angiogenetic process required for endometriosis. In a rat endome…

ObjectiveTo determine the effects of raloxifene and genistein on experimentally induced endometriosis in a rat model.DesignProspective, randomized animal study.SettingAnimal surgery laboratory in a university hospital.Animal(s)Thirty-three …

BACKGROUND: This prospective randomized-controlled animal study was designed to determine the effects of atorvastatin on experimentally induced endometriosis in a rat model. METHODS: Thirty-seven Wistar-Albino rats in which endometriotic im…

In elderly women with osteoporosis, raloxifene treatment with vitamin D supplementation improves vaginal maturation index and vaginal pH.

Study objectiveTo compare tubal sterilization performed by microlaparoscopy and conventional laparoscopy.DesignProspective, randomized trial (Canadian Task Force classification I).SettingGazi University School of Medicine.PatientsTwenty wom…

Study objectiveTo describe a technique of uterine suspension using round ligaments to relieve pain in selected patients with various degrees of uterine retroversion.DesignProspective clinical study (Canadian Task Force classification II-2).…

OBJECTIVE: To investigate the effect of basic fibroblast growth factor (FGF) on preimplantation embryos and to evaluate the levels of basic FGF in follicular and peritoneal fluid. DESIGN: Prospective study. SETTING: University-based laborat…

Proliferation of endometrium is dependent on sex steroid hormones, but specific growth factors are likely to play an important role in regulating this process. A number of cytokines and growth factors are synthesized in the endometrium in r…

PROBLEM: Interleukin-12 (IL-12) is produced mainly by monocytes/macrophages, and it induces proliferation and cytotoxicity of T-cells and natural killer cells. In women with endometriosis, natural killer cell activity in the peritoneal flui…

Abdomino-pelvic adhesions arise from infection, endometriosis, or peritoneal injury during surgery, and represent a significant source of morbidity in women of reproductive age. Monocyte chemotactic protein-1 (MCP-1) plays a role in the che…

The effect of natural, environmental, or manufactured substances on endocrine organs is a current topic of discussion. Recently, some toxicants have been suggested to promote endometriosis; therefore, attention has turned to the role of env…

Serum and peritoneal fluid (PF) CA-125 levels were assayed using the immunoradiometric assay in 17 women with minimal endometriosis and 21 control women at the time of laparoscopy. Serum levels of CA-125 were not significantly higher in wom…