Serum and peritoneal fluid CA-125 levels in early stage endometriosis

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Abstract

Serum and peritoneal fluid (PF) CA-125 levels were assayed using the immunoradiometric assay in 17 women with minimal endometriosis and 21 control women at the time of laparoscopy. Serum levels of CA-125 were not significantly higher in women with minimal endometriosis. Minimal endometriosis was diagnosed with a 70.6% rate of sensitivity and a 71.4% rate of specificity with 16 U/ml as the upper limit of normal. PF CA-125 levels were significantly higher than serum levels but showed no significant difference between control and endometriosis patients.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Tumor-Associated, Carbohydrate Ascitic Fluid Endometriosis Adult Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Ascitic Fluid Endometriosis Female Humans Sensitivity and Specificity

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Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
pubmed
last seen: 2026-05-13T22:12:15.619952+00:00
unpaywall
last seen: 2026-06-14T06:15:46.576397+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine