Daniela Hornung

ORCID: 0000-0003-2351-8235 · 105 papers in corpus
lab-animal 2005
·doi:10.1055/s-2005-920875

Einleitung: Frauen mit Endometriose haben ein erhöhtes Risiko, später ein endometrioides oder klarzelliges Ovarialkarzinom zu entwickeln. Falls Endometriosepatientinnen zusätzlich unter langjähriger Infertilität leiden, erhöht sich die Stan…

2004
·doi:10.1007/s10304-004-0081-6
observational 2004
Fertility and sterility ·doi:10.1016/j.fertnstert.2003.10.026

We explored the association of the PPAR-gamma2 (peroxisome proliferator-activated receptor) Pro-12-Ala polymorphism with endometriosis in a case-control study with 51 women with endometriosis stages I-IV and 55 control women without endomet…

review 2004
·doi:10.3109/9780203319390-14

Cytokines are important mediators of intercellular communication within the immune system. They target a variety of cells and show proliferative, chemoattractant, differentiative, or cytostatic effects. Most cytokines are coupled to intrace…

2004
·doi:10.1007/s00129-003-1478-3
review 2004
·doi:10.1055/s-2004-820951

Die Behandlung der Endometriose konzentriert sich auf zwei Hauptziele: die Verringerung von Schmerzen und die Therapie der Infertilität. Die Schmerztherapie bei Endometriose wurde bisher gut untersucht. So waren alle medikamentösen Behandlu…

2004
·doi:10.1007/s00129-004-1558-z
lab-animal 2003

Eine erhöhte Anzahl von aktivierten Peritonealmakrophagen, die durch Chemokine angezogen werden, sind ein wichtiges pathophysiologisches Merkmal für Frauen mit Endometriose. In dieser Studie charakterisieren wir die inflammatorische Antwort…

2003
·doi:10.1007/s10304-003-0032-7
lab-animal 2003
Gynecologic and obstetric investigation ·doi:10.1159/000068952

Chemoattraction of macrophages into the peritoneal cavity is one of the important characteristics in patients with endometriosis. An inflammatory response is postulated to be responsible for infertility and pelvic pain associated with this …

2002
·doi:10.1016/s0015-0282(01)03091-6
2002
·doi:10.1016/s0889-8561(02)00007-3
2002
·doi:10.1016/s0015-0282(01)03020-5
lab-animal 2002
·doi:10.1055/s-2002-33892

Die Migration von Makrophagen in die Peritonealhöhle ist ein wesentlicher pathophysiologischer Faktor der Endometriose. Frühere Daten aus unserem Labor deuteten darauf hin, dass RANTES (Regulated on Activation, Normal T cell Expressed and S…

lab-animal 2001
Molecular human reproduction ·doi:10.1093/molehr/7.2.163

Endometriotic lesions secrete chemokines that recruit immune cells into the peritoneal cavity. The accumulation of these immune cells, especially activated macrophages and T lymphocytes, is thought to mediate inflammatory symptoms associate…

2001
·doi:10.1016/s0015-0282(01)02205-1
lab-animal 2001
Annals of the New York Academy of Sciences ·doi:10.1111/j.1749-6632.2001.tb03795.x

The human endometrium is a complex tissue comprised of different cell types, including epithelial, stromal, inflammatory, perivascular, and blood vessel cells. The hormonal receptivity and distribution of these cell populations change durin…

other 2001
Fertility and sterility ·doi:10.1016/s0015-0282(00)01791-x

OBJECTIVE: The immunological mechanisms that support persistence and proliferation of ectopic endometrial implants within the peritoneal cavity of women with endometriosis are unknown. Inhibition of natural killer (NK) and cytotoxic T-cell …

lab-animal 2001
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.86.7.7615

The peroxisome proliferator-activated receptors (PPARs) alpha and gamma are nuclear receptors that play important roles in inflammatory diseases like ulcerative colitis and arthritis. In this study, we examined the possible role of PPARs in…

2001
·doi:10.1210/jc.86.7.3108
lab-animal 2001
The American Journal of Pathology ·doi:10.1016/s0002-9440(10)64664-0

Chemoattraction of macrophages and T cells into the normal endometrium and inflammatory sites within endometriotic foci is mediated by chemokine gene expression. mRNA transcripts encoding regulated on activation, normal T-cell-expressed and…

lab-animal 2000

The peroxisome proliferator-activated receptors (PPARs) � and � are nuclear receptors that play important roles in inflammatory diseases like ulcerative colitis and arthritis. In this study, we examined the possible role of PPARs in macroph…

2000
·doi:10.1016/s0015-0282(00)01049-9
other 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.7.6665

Our laboratories have focused recently on the production and localization of eotaxin, a C-C-chemokine of 8.4 kDa, whose major biological activity is the chemoattraction of eosinophils. Given evidence of autoimmune activity in the endometrio…

1999

The assessment of the activity of endometriosis provides a challenge during endoscopic procedures. Novel approaches can be developed in future based on more detailed understanding of the mechanisms of the pathogenesis of endometriosis. Angi…