Tanikawa M

No ORCID on file · 14 papers in corpus · active 1989-2024

Study types

  • article 4
  • other 3
  • editorial 1

Condition tags

  • endometriosis 8
2024
Scientific reports ·doi:10.1038/s41598-024-69796-4

The cellular origin of clear cell ovarian carcinoma (CCOC), a major histological subtype of ovarian carcinoma remains elusive. Here, we explored the candidate cellular origin and identify molecular subtypes using integrated genomic/epigenom…

2023
Scientific reports ·doi:10.1038/s41598-023-47637-0

The purpose of this study is to clarify the metabolic dependence of ovarian clear cell carcinoma (CCC) by comparing normal tissues and to examine the applicability of fluorescence imaging probe to exploit these metabolic differences. Enhanc…

article 2022
BMC women's health ·doi:10.1186/s12905-022-01917-5

BACKGROUND: Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes…

2020
Oncology letters ·doi:10.3892/ol.2020.12014

Previous studies have suggested that histone methylation can modulate carcinogenesis and cancer progression. For instance, the histone methyltransferase SET and MYND domain containing 2 (SMYD2) is overexpressed in several types of cancer ti…

2019
BMC cancer ·doi:10.1186/s12885-019-5638-9

BackgroundWolf-Hirschhorn syndrome candidate gene-1 (WHSC1), a histone methyltransferase, has been found to be upregulated and its expression to be correlated with expression of enhancer of zeste homolog 2 (EZH2) in several cancers. In this…

2015
PloS one ·doi:10.1371/journal.pone.0128066

Ovarian clear cell carcinoma (CCC) is generally associated with chemoresistance and poor clinical outcome, even with early diagnosis; whereas high-grade serous carcinomas (SCs) and endometrioid carcinomas (ECs) are commonly chemosensitive a…

2014
PloS one ·doi:10.1371/journal.pone.0087220

DS-7423, a novel, small-molecule dual inhibitor of phosphatidylinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR), is currently in phase I clinical trials for solid tumors. Although DS-7423 potently inhibits PI3Kα (IC50 = 15.…

editorial 2000
Fertility and Sterility ·doi:10.1016/s0015-0282(99)00496-3

ObjectiveTo compare the expression of interleukin-6 (IL-6) in endometrial and endometriotic cells.DesignProspective study.SettingDepartment of Obstetrics and Gynecology, Tottori University Hospital, Yonago, Japan.Patient(s)Twenty patients w…

other 2000
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.85.2.6335

Endometriosis, a common disease among women of reproductive age, is characterized by the presence of endometrial-like tissue outside the uterus. We and others showed that several cytokine levels, including interleukin-8 (IL-8) and tumor nec…

other 1999
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(99)70599-5

OBJECTIVE: This study investigated the possible roles of interleukin 6 and soluble interleukin 6 receptor in the growth of endometrial and endometriotic cells. STUDY DESIGN: Endometrial and endometriotic stromal cells were collected from t…

article 1999
Gynecologic and obstetric investigation ·doi:10.1159/000052857

Peritoneal fluid in women with endometriosis contains an increased number of activated macrophages that secrete a variety of cytokines, including interleukin (IL)-6, IL-8, vascular endothelial growth factor, and tumor necrosis factor-alpha …

article 1998
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00049-1

ObjectiveTo investigate the role of interleukin-8 (IL-8) in peritoneal fluid of patients with endometriosis in the pathogenesis of endometriosis.DesignPeritoneal fluid was collected by laparoscopy. Endometrial and endometriotic stromal cell…

article 1997
American Journal of Obstetrics and Gynecology ·doi:10.1016/s0002-9378(97)70553-2

ObjectiveOur purpose was to investigate the relationship between the levels of interleukin-6, interleukin-6 soluble receptor, and tumor necrosis factor-alpha in peritoneal fluid and the size and number of active red endometriotic lesions.St…

other 1989
Nihon Sanka Fujinka Gakkai zasshi

In order to evaluate the effectiveness and safety of ultrasonic oocyte collection for IVF-ET, a comparative study was performed on the results of IVF-ET by the transabdominal and transvaginal methods in 145 cycles of 51 patients. The oocyte…