Study types
- other 3
- article 2
- review 1
Condition tags
- endometriosis 6
- die_deep_infiltrating 2
- endometrioma 1
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BACKGROUND: Ovarian clear cell carcinoma (OCCC) is an endometriosis-associated ovarian cancer subtype. Somatic mutations in OCCC are reported in ARID1A, PIK3CA, and the TERT promoter (TERTp), as well as less commonly in KRAS and TP53 among …
STUDY QUESTION: Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology? SUMMARY ANSWE…
BACKGROUND: Endometriosis is a chronic, heterogeneous disease with limited non-hormonal treatment options. Drug repurposing provides an accelerated route to identify safe, tolerable, and potentially effective therapies for endometriosis. Re…
As a heterogenous disease with likely multiple pathogeneses and as-yet-undefined subtypes, progress in endometriosis treatment is currently limited by a lack of appropriate models and cohorts for research. Almost half of all publicly availa…
STUDY QUESTION: Is circulating cell-free DNA (cirDNA) from the endometrium elevated during menstruation and in endometriosis? SUMMARY ANSWER: Endometrial cirDNA does not increase during menstruation and is not elevated in endometriosis. W…