STUDY QUESTION: Is circulating cell-free DNA (cirDNA) from the endometrium elevated during menstruation and in endometriosis? SUMMARY ANSWER: Endometrial cirDNA does not increase during menstruation and is not elevated in endometriosis. W…
Oocyte-secreted growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are critical paracrine regulators of female fertility. Recent studies demonstrated that serum concentrations are associated with the number of …
Research questionDo women with laparoscopically confirmed endometriosis have higher plasma concentrations of circulating cell-free DNA (cirDNA) than those without endometriosis?DesignProspective study of women aged 18-45 years undergoing be…
Endometriosis is a condition in which functional endometrial glands are located outside the uterine cavity. Common sites are the pelvic peritoneum, the ovaries, uterine ligaments and rectovaginal septum.
Hydrosalpinx is a fluid accumulation in the fallopian tube which has become blocked, at the fimbrial end and the isthmus. This blockage can be caused by infection, sexually transmitted disease, previous sterilisation, endometriosis or surge…