Sieberg CB

No ORCID on file · 20 papers in corpus · active 2020-2026

Study types

  • article 7
  • other 7
  • preprint 2

Condition tags

  • endometriosis 15
  • chronic_pelvic_pain 14
  • dysmenorrhea 5
  • dyspareunia 4
  • interstitial_cystitis 3
  • irritable_bowel_syndrome 1
other 2026
Reproduction & fertility ·doi:10.1530/RAF-25-0091

ABSTRACT: We explore bladder sensitivity profiles in females with chronic pelvic pain, using a non-invasive bladder sensitivity paradigm. We aim to determine how profiles differ between groups defined by symptoms; groups defined by diagnose…

other 2026
Pain ·doi:10.1097/j.pain.0000000000003857

Chronic pelvic pain (CPP) is a common and burdensome symptom in women yet current clinical management frequently leaves many with persistent pain. The Translational Research in Pelvic Pain (TRiPP) project adopts a pain-focused strategy, aim…

other 2025
Communications biology ·doi:10.1038/s42003-025-08952-6

Endometriosis is a highly prevalent and often painful gynecological condition that can emerge in adolescence and can be experienced throughout a person's lifetime. This cross-sectional investigation performed structural brain imaging and a …

article 2025
Frontiers in pain research (Lausanne, Switzerland) ·doi:10.3389/fpain.2025.1439563

BACKGROUND: Conditioned pain modulation (CPM) is considered a human proxy for descending inhibitory pain pathways. However, there is wide variation in the CPM response described in the literature and ongoing debate about its utility. METHO…

2025
Scientific reports ·doi:10.1038/s41598-025-00685-0

Chronic post-surgical pain (CPSP) poses significant socioeconomic and humanitarian challenges. This study investigated relationships between resting-state neural activation in the somatosensory cortex (SMC) and emotional functioning outcome…

article 2024
Frontiers in reproductive health ·doi:10.3389/frph.2023.1306380

INTRODUCTION: Over four million women in the US alone have been diagnosed with endometriosis. For those living with this disease, surgery and hormonal treatment reduce associated pelvic pain in some, while others continue to experience life…

other 2024
F1000Research ·doi:10.12688/f1000research.141793.1

Background: While the majority of reproductive-aged females will experience pelvic pain during their lives, biological mechanisms underlying pelvic pain are not well understood. We investigated associations between pelvic pain symptoms and …

other 2024
Pain ·doi:10.1097/j.pain.0000000000003001

Abdominal pain is a common symptom of several debilitating conditions (eg, inflammatory bowel disease, irritable bowel syndrome, and endometriosis) and affects individuals throughout their lifespan. Quantitative sensory testing (QST) refere…

article 2024
Pain ·doi:10.1097/j.pain.0000000000003218

Chronic pelvic pain is heterogeneous with potentially clinically informative subgroups. We aimed to identify subgroups of pelvic pain based on symptom patterns and investigate their associations with inflammatory and chronic pain-related co…

other 2024
BJOG: An International Journal of Obstetrics & Gynaecology ·doi:10.1111/1471-0528.17915

OBJECTIVE: To quantify the variation, triggers and impact on quality of life of symptom flares in women with chronic pelvic pain (CPP). DESIGN: Cross-sectional questionnaire within the Translational Research in Pelvic Pain clinical cohort …

2023
Neurophotonics ·doi:10.1117/1.nph.10.2.025014

SignificanceQuantitative measurement of perisurgical brain function may provide insights into the processes contributing to acute and chronic postsurgical pain.AimWe evaluate the hemodynamic changes in the prefrontal cortex (medial frontopo…

article 2023
Frontiers in reproductive health ·doi:10.3389/frph.2023.1140857

INTRODUCTION: Chronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid con…

other 2023
Pain ·doi:10.1097/j.pain.0000000000002955

Chronic pelvic pain (CPP), despite its high prevalence, is still relatively poorly understood mechanistically. This study, as part of the Translational Research in Pelvic Pain (TRiPP) project, has used a full quantitative sensory testing (Q…

article 2023
Human Reproduction ·doi:10.1093/humrep/dead099

STUDY QUESTION: What are the similarities and differences in the systemic proteomic profiles by endometriosis-associated pain subtypes among adolescents and young adults with endometriosis? SUMMARY ANSWER: Endometriosis-associated pain sub…

2023
Frontiers in pain research (Lausanne, Switzerland) ·doi:10.3389/fpain.2023.1223239

IntroductionQuantitative sensory testing (QST) is often used to understand the perceptual basis of acute and chronic conditions, including pain. As the need grows for developing a mechanistic understanding of neurological pathways underlyin…

preprint 2022
·doi:10.1101/2022.10.03.22280515

Abstract Chronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation is varied and there are frequently comorbid conditio…

preprint 2022
·doi:10.1101/2022.05.16.22274828

Abstract Objectives Chronic pelvic pain is common, poorly understood, and many women suffer for years without proper diagnosis and effective treatment. The Translational Research in Pelvic Pain (TRiPP) project takes a phenotyping approach, …

article 2022
Pain ·doi:10.1097/j.pain.0000000000002747

We described trends in pelvic pain characteristics over 2 years of follow-up among adolescents and adults with and without endometriosis participating in the longitudinal observational cohort of the Women's Health Study: From Adolescence to…

2021
Frontiers in reproductive health ·doi:10.3389/frph.2021.670919

Awareness and visibility of transgender individuals have grown exponentially. However, conceptualizing sexual and reproductive health (SRH) as "women's" or "men's" health services further marginalizes transgender and gender-expansive (TGE) …

article 2020

Claire E Lunde, 1– 3,* Edina Szabo, 1, 4,* Scott A Holmes, 1, 4 David Borsook, 1, 4 Christine B Sieberg 1, 2, 5 1Center for Pain and the Brain (P.A.I.N. Group), Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children…