Gao S

INTRODUCTION: Serous surface papillary borderline ovarian tumors (SSPBOTs), a clinically distinct variant of serous borderline ovarian tumors (SBOTs), are frequently misdiagnosed as malignant tumors during preoperative diagnostic assessment…

INTRODUCTION: Endometriosis, a chronic gynecological disorder, significantly impacts fertility and quality of life. Identifying effective therapeutic targets is critical for their management. OBJECTIVES: The objective of this study was to …

[This corrects the article DOI: 10.1016/j.pscia.2026.100109.].

Ferroptosis is a form of programmed cell death characterized by iron-dependent phospholipid peroxidation and is implicated in a wide range of human diseases. Emerging evidence highlights the critical role of epigenetic regulation in this pr…

BACKGROUND: Homocysteine (Hcy) is a sulfur-containing intermediate metabolite during methionine metabolism. Studies indicate that individuals with polycystic ovary syndrome (PCOS) have higher circulating Hcy levels relative to unaffected po…

Endometriosis is a common gynecological disorder in which inflammatory and immune responses play a crucial role in its development and progression. This study aimed to identify potential inflammation-related biomarkers for the diagnosis and…

Polycystic ovary syndrome (PCOS) is a common reproductive and metabolic disorder with a complex and yet unresolved etiology. Although ovulation induction therapy can improve ovulatory function, the natural pregnancy rate and pregnancy outco…

Adenomyosis remains a challenging gynecological disorder to investigate due to the absence of in vitro models that accurately replicate endometrial tissue dynamics across the menstrual cycle. To address this gap, we established an endometri…

INTRODUCTION: Chronic pelvic pain (CPP) is a common condition involving multiple systems, characterized by complex manifestations and diverse clinical symptoms. The current treatment options for CPP are limited and may be only effective for…

OBJECTIVE: This study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer. MATERIALS AND METHODS: This study included 133 patients who were treated at Beijing Obstetric…

BACKGROUND: Opioid-free anesthesia (OFA) protocols using esketamine and dexmedetomidine have shown potential benefits for perioperative pain control with fewer side effects. We explored whether an esketamine–dexmedetomidine OFA regimen acce…

INTRODUCTION: Cisplatin resistance is a major challenge in ovarian cancer therapy, particularly for high-grade serous ovarian cancer (HGSOC). DNA topoisomerase IIα (TOP2A) relates to cancer drug resistance, yet its role and molecular mechan…

The VDR and MTHFR polymorphisms have been linked to many gynecological and obstetrical diseases. However, there is still a pressing need for a systematic review and meta-analysis to synthesize the current evidence on the association between…

Irpex lacteus is a fungus typically found on angiosperm branches and trunks. Here, we report the isolation of a novel strain of I. lacteus from the cervix uteri of a female patient diagnosed with endometriosis and COVID-19 at Beijing Obstet…

BACKGROUND: Ovarian cancer (OC) is a heterogeneous malignancy with multiple histological subtypes, showing global variability in incidence. Temporal changes in diagnostic criteria and risk factors might influence the incidence and distribut…

The incidence of patients diagnosed with either breast cancer (BC) or inflammatory bowel disease (IBD) is increasing each year. IBD has been shown to be strongly associated with the development of a variety of solid tumors, but the relation…

Gastric-type endocervical adenocarcinoma (GAS) is a rare non-human papillomavirus associated mucinous adenocarcinoma of the cervix. Its clinical manifestations are extremely atypical, with hidden lesions and difficulty in obtaining material…

BACKGROUND: The triglyceride glucose (TyG) index has been well recognized as a reliable marker of insulin resistance and substantially correlated with the pathogenesis and progression of hypertension and cardiovascular diseases. However, no…

Luteolin is a kind of natural flavonoid, widely existing in a variety of plants, has been revealed to have a wide range of biological activities. In recent years, the research results of luteolin are abundant. Here we review the latest rese…

Estrogen is thought to have a role in slowing down aging and protecting cardiovascular and cognitive function. However, high doses of estrogen are still positively associated with autoimmune diseases and tumors with systemic inflammation. F…

PURPOSE: To evaluate the insulin resistance in patients with menopause who were newly diagnosed with endometrial cancer and its association with disease development. METHODS: The study included 356 patients with menopause who underwent hys…

Premature ovarian insufficiency (POI) is a serious disease significantly affecting the physical and mental health of women of reproductive age, not just impacting fertility outcomes. Ovarian damage due to chemotherapy remains a major cause …

BACKGROUND: Embryonic ploidy is critical for the success of embryo transfer. Currently, preimplantation genetic testing for aneuploidy (PGT-A) is the gold standard for detecting ploidy abnormalities. However, PGT-A has several inherent limi…