Hauser R

BACKGROUND: Personal care products (PCPs) may contain endocrine-disrupting chemicals (EDCs) that can impact menstrual health. Despite widespread usage, little is known about the associations of PCP usage, EDC avoidance, and menstrual cycle …

BackgroundPolycystic ovary syndrome is a common endocrine disorder, characterized by oligomenorrhea and androgen excess. Only a few studies have addressed the natural history of menstrual cycles among women with polycystic ovary syndrome an…

Background/objectivesFew studies have investigated the association of dietary glycemic index (GI), glycemic load (GL), and carbohydrate intake with antral follicle count (AFC). This study aimed to investigate the association of total carboh…

BACKGROUND: Using menstrual products is a part of managing menstrual bleeding. Product use may represent individual, social, and economic influences. A few studies on menstrual product use from specific regions in the United States reported…

Study questionCan algorithms using wrist temperature, available on compatible models of iPhone and Apple Watch, retrospectively estimate the day of ovulation and predict the next menses start day?Summary answerAlgorithms using wrist tempera…

Exposure to phthalates is common and difficult to avoid. However, intake of long-chain n-3 polyunsaturated fatty acids (n3PUFAs) may ameliorate negative effects on ovarian reserve by exposure to phthalates as both are involved in key proces…

PurposeTo determine correlations between chemicals in follicular fluid (FF) and follicular reproductive hormone levels.MethodsThe analysis was part of a larger cohort study to determine associations between exposure to EDCs and in vitro fer…

BACKGROUND: Use of menstrual tracking data to understand abnormal bleeding patterns has been limited because of lack of incorporation of key demographic and health characteristics and confirmation of menstrual tracking accuracy. OBJECTIVE:…

ObjectiveTo investigate the association between intake of soy food and isoflavone with ovarian reserve. Previous studies suggest on the relationship between soy intake and human fertility are inconsistent. Some clinical studies suggest that…

Study questionIs there an association between iron intake and ovarian reserve among women seeking fertility care?Summary answerSupplemental iron intake above 45 mg/day is associated with lower ovarian reserve among women seeking fertility c…

PurposeTo compare the expression profile of extracellular vesicle microRNAs (EV-miRNAs) derived from follicular fluid after a trigger with recombinant human chorionic gonadotropin (r-hCG) or with a gonadotropin-releasing hormone GnRH agonis…

ObjectiveTo compare the variability in metabolomes between the serum and follicular fluid, as well as across 3 dominant follicles.DesignProspective cohort study.SettingAn academic fertility clinic in the northeastern United States, 2005-201…

BackgroundProspective longitudinal cohorts assessing women's health and gynecologic conditions have historically been limited.ObjectiveThe Apple Women's Health Study was designed to gain a deeper understanding of the relationship among mens…

BackgroundPhthalates are endocrine-disrupting chemicals that are widely present in consumer products. In the United States, Black women are more highly exposed to phthalates than other racial/ethnic groups, yet information on predictors of …

BackgroundFew epidemiologic studies have evaluated the impact of paternal environmental exposures, particularly as mixtures, on couples' pregnancy outcomes.ObjectiveWe investigated whether mixtures of paternal urinary bisphenol A (BPA), par…

BackgroundInfertility affects 15%-25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has b…

Exposure to phthalates, endocrine-disrupting chemicals commonly used as plasticizers and in consumer products, has been associated with infertility and premature ovarian failure. Our objective was to investigate whether urinary phthalate me…

Accumulating evidence suggests that air pollution increases pregnancy loss; however, most previous studies have focused on case identification from medical records, which may underrepresent early pregnancy losses. Our objective was to inves…

BackgroundQuinolinic acid (QA), a neuroactive metabolite produced during tryptophan degradation, is implicated in the pathogenesis of several neurological disorders. Phthalates are structurally similar to QA, and exposure to phthalates has …

PurposeTo enhance the understanding of the clinical significance of anti-Müllerian hormone (AMH) in follicular fluid, we aimed to determine the variability of AMH concentrations in follicular fluid within and across IVF cycles and whether h…

PurposeTo assess whether machine learning methods provide advantage over classic statistical modeling for the prediction of IVF outcomes.MethodsThe study population consisted of 136 women undergoing a fresh IVF cycle from January 2014 to Au…

BackgroundSubfertile women have higher risk of glucose intolerance during pregnancy. Studies suggest associations between several endocrine disrupting chemicals (EDCs) and pregnancy glucose levels. However, the association between benzophen…

ObjectiveTo study whether increased body mass index is associated with altered expression of extracellular vesicle microRNAs (EV-linked miRNAs) in human follicular fluid.DesignCross-sectional study.SettingTertiary-care university-affiliated…

BackgroundAn increasing number of studies have linked air pollution to decreased fertility. Whether this is due to an effect on ovarian reserve is unknown.MethodOur study included 632 women attending the Massachusetts General Hospital Ferti…

BackgroundRandomized trials of supplementation with antioxidant mixtures during infertility treatment show no benefit on pregnancy or live birth rate. However, the roles of individual antioxidants are poorly understood. We examined the asso…