Toth TL

PurposeWe sought to determine whether pregnancies conceived in those with male factor infertility have unique placental pathology profiles compared to those undergoing infertility treatments for other indications.MethodsThis was a retrospec…

A mediator is a factor that occurs after the exposure of interest, precedes the outcome of interest (i.e. between the exposure and the outcome) and is associated with both the exposure and the outcome of interest (i.e. is on the pathway bet…

ImportanceAnimal experiments suggest that ingestion of pesticide mixtures at environmentally relevant concentrations decreases the number of live-born offspring. Whether the same is true in humans is unknown.ObjectiveTo examine the associat…

BackgroundThe Environment and Reproductive Health (EARTH) Study is an ongoing prospective preconception cohort designed to investigate the impact of environmental, nutritional, and lifestyle factors among both women and men on fertility and…

BackgroundCigarette smoking has been associated with worse infertility treatment outcomes, yet some studies have found null or inconsistent results.MethodsWe followed 225 couples who underwent 354 fresh non-donor assisted reproductive techn…

Much of the literature on the impact of male caffeine and alcohol intake on reproductive outcomes has utilized semen quality as a proxy for male fertility, although semen parameters have a limited predictive value for spontaneous pregnancy.…

Study questionIs pre-treatment alcohol and caffeine intake associated with infertility treatment outcomes among women undergoing ART?Summary answerLow to moderate alcohol and caffeine intakes in the year prior to infertility treatment were …

ObjectiveTo evaluate the relationship between pretreatment intake of whole grains and outcomes of IVF.DesignProspective cohort study.SettingAcademic medical center.Patient(s)A total of 273 women who collectively underwent 438 IVF cycles.Int…

ObjectiveTo explore the relationship between urinary paraben concentrations and IVF outcomes among women attending an academic fertility center.DesignProspective cohort study.SettingFertility clinic in a hospital setting.Patient(s)A total o…

BackgroundPreconceptional folate and vitamin B-12 have been linked to beneficial reproductive outcomes in both natural pregnancies and those after assisted reproductive technology (ART) treatment.ObjectiveThe objective of the study was to e…

Total hair mercury (Hg) was measured among 205 women undergoing in vitro fertilization (IVF) treatment and the association with prospectively collected IVF outcomes (229 IVF cycles) was evaluated. Hair Hg levels (median=0.62ppm, range: 0.03…

Male factor etiology may be a contributing factor in up to 60% of infertility cases. Dietary intake of phytoestrogens has been related to abnormal semen quality and hormone levels. However, its effect on couple fecundity is still unclear. I…

ObjectiveTo study the relation of dietary phytoestrogens intake and clinical outcomes of women undergoing infertility treatment with the use of assisted reproductive technology (ART).DesignProspective cohort study.SettingFertility center.Pa…

ObjectiveTo prospectively evaluate the associations of folate with assisted reproductive technology outcomes within a population in the United States.MethodsThis analysis included women (n=232) in a prospective cohort study at the Massachus…

PurposeTo evaluate pregnancy rate (PR) and live birth rate (LBR) after freezing pronuclear (PN) embryos for two purposes: to reduce the risk of ovarian hyperstimulation syndrome (OHSS) and to bank embryos for cancer patients anticipating ga…

PurposeThe impact of severity of endometriosis on the outcome of in vitro fertilization (IVF) was analyzed in an uncontrolled, retrospective study in an academic IVF program.MethodsSixty-one patients with a primary diagnosis of endometriosi…

CONTEXT: Short-term intermittent administration of parathyroid hormone (PTH) prevents bone loss from the spine in women treated with a gonadotropin-releasing hormone (GnRH) analog. However, the effects of a longer period of PTH administrati…

PurposeThe outcome of in vitro fertilization (IVF) in a group of infertile women with a history of in utero exposure to diethylstilbestrol (DES) was analyzed. Records from an academic IVF program were retrospectively reviewed.MethodsSevente…