Dian Tjahyadi

BACKGROUND: The etiology of adenomyosis remains uncertain, and factors such as pregnancy, postpartum endometritis, cesarean delivery, uterine surgery, and uterine trauma are suspected to cause myometrial disruption that may trigger smooth m…

Background: Adenomyosis is a major cause of chronic pelvic pain in women of reproductive age and significantly affects quality of life. Identifying biomarkers associated with pain mechanisms may improve understanding of disease pathophysiol…

Endometriosis is an enigmatic disease affecting approximately 10% of the population. This unique disease is often chronic and characterized by inflammation. Even though endometriosis and its related disease, adenomyosis, are benign tumors, …

Background: Endometriosis is a chronic gynecological disorder characterized by the presence of endometrium-like tissue outside the uterine cavity. It is most commonly found in the pelvic organs but may also occur in extrapelvic sites, inclu…

Dian Tjahyadi, Aisyah Shofiatun Nisa, Hartanto Bayuaji, Gatot Nyarumenteng Adhipurnawan Winarno, Ruswana Anwar Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Ban…

Background: Endometriosis is a chronic inflammatory condition, causing severe pelvic pain, organ dysfunction, infertility, and mental health issues. Ovarian reserve, indicating the quantity and quality of a woman's oocytes, is negatively af…

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissues (glands and stroma) located outside the uterine cavity. The pathophysiology of this condition remains incompletely understood. Local b…

Background: Adenomyosis is a benign uterine disease characterized by the presence of endometrial glands and stroma in the myometrium.It lacks classic physical or laboratory examination findings, which hinders clinical diagnosis.Although unl…

BACKGROUND: Elagolix, Linzagolix, and Relugolix, as oral gonadotropin-releasing hormone antagonists, have emerged as promising treatments for endometriosis-associated pain. OBJECTIVE: To evaluate pain intensity reduction as the primary out…

Objective: This study aims to translate, develop, and assess the validity and reliability of the Indonesian version of Professor Chapron’s screening method for endometriosis diagnosis based on the questionnaire as a tool for better endometr…

Introduction: Adenomyosis, a benign uterine condition characterized by endometrial tissue within the myometrium, leads to uterine enlargement, infertility, dysmenorrhea, and heavy menstrual bleeding. While its precise etiology remains elusi…

OBJECTIVE: This study aimed to investigate the levels of chitinase-3-like protein-1 (CHI3L1), matrix metalloproteinase-9 (MMP-9), and monocyte chemoattractant protein-1 (MCP-1) in adenomyosis, as compared to normal myometrial tissue. These …

Background: Adenomyosis is a gynaecological condition characterized by the infiltration of endometrial glands and stroma resulting in ectopic intramyometrial, leading to the generalized enlargement of the uterus. Various cyclical regimens a…

INTRODUCTION: Adenomyosis (benign gynecological disease) is an endometrial stromal tissue condition that invades the myometrium of the uterus. The administration of a gonadotropin-releasing hormone (GnRH) analog before the IVF (In Vitro Fer…